| Vial description: |
ALK5, SKR4, TGF-beta type I receptor, TGFR-1, TbetaR-I, TGF-beta receptor type-1 |
| Category: |
primary antibody |
| Raised in: |
Rabbit |
| Clone: |
1 vial |
| Form: |
Affinity Purified |
| Reactivity: |
Human, Mouseorcine, Rat, Bovine |
| Purity: |
purified |
| Molecular weight: |
in kDa |
| Source: |
mammalian |
| Activity: |
to be determined |
| Range: |
broad |
| Protein number: |
P36897 |
| Application: |
Western Blot |
| Storage: |
Avoid freeze/thaw cycles, Upon delivery aliquot and store at -20°, C, C for one year, Shipped at 4° |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by acr they should be stored frozen at - 24° |
| Gene target: |
TGFBR1 / ALK-5 |
| Short name: |
anti-TGFBR1 / ALK-5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
b receptor 1 / anaplastic lymphoma receptor tyrosine kinase-5 (Antibody to), antibody to-transforming growth factor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AAT5 and ACVRLK4 and ALK-5 and ALK5 and ESS1 and LDS1 and LDS1A and LDS2A and MSSE and SKR4 and TGFR-1, ALK and IDBG-42084 and ENSG00000171094 and 238, ALK and IDBG-636042 and ENSBTAG00000007379 and 536642, Alk and IDBG-197259 and ENSMUSG00000055471 and 11682, CD246 and NBLST3, Cell surfaces, DNA-templated and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007165 and signal transduction and biological process this GO :0007178 and transmembrane receptor protein serine/threonine kinase signaling pathway and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007507 and heart development and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008354 and germ cell migration and biological process this GO :0009435 and NAD biosynthetic process and biological process this GO :0009791 and post-embryonic development and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016772 and transferase activity, DNA-templated and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0048538 and thymus development and biological process this GO :0048663 and neuron fate commitment and biological process this GO :0048701 and embryonic cranial skeleton morphogenesis and biological process this GO :0048705 and skeletal system morphogenesis and biological process this GO :0048762 and mesenchymal cell differentiation and biological process this GO :0048844 and artery morphogenesis and biological process this GO :0048870 and cell motility and biological process this GO :0050431 and transforming growth factor beta binding and molecular function this GO :0051272 and positive regulation of cellular component movement and biological process this GO :0051491 and positive regulation of filopodium assembly and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0060017 and parathyroid gland development and biological process this GO :0060021 and palate development and biological process this GO :0060037 and pharyngeal system development and biological process this GO :0060389 and pathway-restricted SMAD protein phosphorylation and biological process this GO :0060391 and positive regulation of SMAD protein import into nucleus and biological process this GO :0070022 and transforming growth factor beta receptor homodimeric complex and cellular component this GO :0070411 and I-SMAD binding and molecular function this GO :0070723 and response to cholesterol and biological process this GO :0071560 and cellular response to transforming growth factor beta stimulus and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process, Plasma membranes, TGFBR1 and IDBG-634152 and ENSBTAG00000018035 and 282382, TGFBR1 and IDBG-78488 and ENSG00000106799 and 7046, Tgfbr1 and IDBG-146050 and ENSMUSG00000007613 and 21812, beta receptor 1, this GO :0000186 and activation of MAPKK activity and biological process this GO :0001501 and skeletal system development and biological process this GO :0001525 and angiogenesis and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001822 and kidney development and biological process this GO :0001824 and blastocyst development and biological process this GO :0001837 and epithelial to mesenchymal transition and biological process this GO :0001937 and negative regulation of endothelial cell proliferation and biological process this GO :0002088 and lens development in camera-type eye and biological process this GO :0004514 and nicotinate-nucleotide diphosphorylase (carboxylating) activity and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004675 and transmembrane receptor protein serine/threonine kinase activity and molecular function this GO :0004702 and receptor signaling protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005024 and transforming growth factor beta-activated receptor activity and molecular function this GO :0005025 and transforming growth factor beta receptor activity, this GO :0000187 and activation of MAPK activity and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004704 and NF-kappaB-inducing kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007399 and nervous system development and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016310 and phosphorylation and biological process this GO :0016772 and transferase activity, this GO :0004514 : nicotinate-nucleotide diphosphorylase (carboxylating) activity, this GO :0004514 : nicotinate-nucleotide diphosphorylase (carboxylating) activity and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004675 : transmembrane receptor protein serine/threonine kinase activity and also this GO :0004702 : receptor signaling protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005024 : transforming growth factor beta-activated receptor activity and also this GO :0005025 : transforming growth factor beta receptor activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004704 : NF-kappaB-inducing kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004675 : transmembrane receptor protein serine/threonine kinase activity, this GO :0004702 : receptor signaling protein serine/threonine kinase activity, this GO :0004704 : NF-kappaB-inducing kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0005024 : transforming growth factor beta-activated receptor activity, this GO :0005025 : transforming growth factor beta receptor activity, this GO :0005114 : type II transforming growth factor beta receptor binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0016772 : transferase activity, this GO :0019838 : growth factor binding, this GO :0046332 : SMAD binding, this GO :0046872 : metal ion binding, this GO :0050431 : transforming growth factor beta binding, this GO :0070411 : I-SMAD binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019838 : growth factor binding and also this GO :0046332 : SMAD binding and also this GO :0046872 : metal ion binding and also this GO :0050431 : transforming growth factor beta binding and also this GO :0070411 : I-SMAD binding, transferring phosphorus-containing groups and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0018107 and peptidyl-threonine phosphorylation and biological process this GO :0019838 and growth factor binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030199 and collagen fibril organization and biological process this GO :0030307 and positive regulation of cell growth and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0031396 and regulation of protein ubiquitination and biological process this GO :0032331 and negative regulation of chondrocyte differentiation and biological process this GO :0042060 and wound healing and biological process this GO :0043062 and extracellular structure organization and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043235 and receptor complex and cellular component this GO :0043393 and regulation of protein binding and biological process this GO :0043542 and endothelial cell migration and biological process this GO :0045893 and positive regulation of transcription, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0038061 and NIK/NF-kappaB signaling and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043234 and protein complex and cellular component this GO :0046777 and protein autophosphorylation and biological process this GO :0048666 and neuron development and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, transforming growth factor, transforming growth factor beta receptor activity, type I, type I and also this GO :0005114 : type II transforming growth factor beta receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, type I and molecular function this GO :0005114 and type II transforming growth factor beta receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005923 and tight junction and cellular component this GO :0006355 and regulation of transcription, anaplastic lymphoma receptor tyrosine kinase |
| Identity: |
11772 |
| Gene: |
TGFBR1 |
More about : TGFBR1 |
| Long gene name: |
transforming growth factor beta receptor 1 |
| Synonyms gene: |
MSSE ESS1 |
| Synonyms gene name: |
multiple self-healing squamous epithelioma transforming growth factor beta receptor I |
| Synonyms: |
ALK-5 ACVRLK4 ALK5 |
| Synonyms name: |
53kDa , activin A receptor type II-like kinase |
| Locus: |
9q22, 33 |
| Discovery year: |
1993-09-30 |
| Entrez gene record: |
7046 |
| Pubmed identfication: |
1319842 8530052 21358634 |
| Classification: |
Type 1 receptor serine/threonine kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000020353 |
| Locus Specific Databases: |
Belgium , Ghent, LOVD - Center for Medical Genetics |