| Long name: |
GPX2/Glutathione Peroxidase 2 Antibody |
| Also known as: |
GPX2/Glutathione Peroxidase 2 Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GPX2/Glutathione Peroxidase 2 |
| Specificity: |
This is a highly specific antibody against GPX2/Glutathione Peroxidase 2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GPX2/Glutathione Peroxidase 2 |
| Gene ID number: |
2877 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
GPx enzymes reduce lipid hydroperoxides to alcohols, GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, GPx-1 plays an important role in the antioxidant defense of the vascular wall and neural cells in response to oxidative stress, GPx-2 is the major isoform in the lungs and its basal or inducible expression is dependent on Nrf2, GPx-3 is under regulation by hypoxic stress and the expression and deficiency of GPx-3 is associated with cardiovascular disease and stroke, GPx-5 is selenium-independent, There are eight GPx homologs (GPx-1â, and reduce free hydrogen peroxide to water, it is bound to the acrosome of sperm, where it may protect sperm from premature acrosome reaction in the epididymis, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA, &euro, &ldquo, 8), Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GI GPx, GPRP, GPRP-2, GPX2, GPX2_HUMAN, GPx 2, GPx-2, GPx-GI, GSHPx 2, GSHPx GI, GSHPx-2, GSHPx-GI, Glutathione peroxidase 2, Glutathione peroxidase 2 gastrointestinal, Glutathione peroxidase gastrointestinal, Glutathione peroxidase related protein 2, Glutathione peroxidase-gastrointestinal, Glutathione peroxidase-related protein 2, Gastrointestinal glutathione peroxidase |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GPX2/Glutathione 2 |
| Short name: |
GPX2/Glutathione Peroxidase 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GPX2/GSH Peroxidase 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4554 |
| Gene: |
GPX2 |
More about : GPX2 |
| Long gene name: |
glutathione peroxidase 2 |
| Synonyms gene name: |
glutathione peroxidase 2 (gastrointestinal) |
| Synonyms: |
GSHPX-GI |
| Locus: |
14q23, 3 |
| Discovery year: |
1993-05-03 |
| Entrez gene record: |
2877 |
| Pubmed identfication: |
8428933 8287691 |
| Classification: |
Selenoproteins |
| Havana BLAST/BLAT: |
OTTHUMG00000171677 |