| Long name: |
ALEXA FLUOR 647 Conjugated, Glutaredoxin 2 Polyclonal Antibody |
| Also known as: |
Anti-Glutaredoxin 2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Glutaredoxin 2 |
| Specificity: |
This is a highly specific antibody against Glutaredoxin 2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
120-164/164 |
| Subcellular location: |
Mitochondrion, Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Glutaredoxin 2 |
| Gene ID Number: |
51022 |
| Swiss Prot: |
Q9NS18 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides, Can receive electrons not only from glutathione (GSH), Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress, Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release, but also from thioredoxin reductase supporting both monothiol and dithiol reactions, which in turn regulates the superoxide production by the complex, Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Glutaredoxin 2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Glutaredoxin 2 |
| Short name: |
Glutaredoxin 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Glutaredoxin 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18376 |
| Gene: |
GLRXP2 |
More about : GLRXP2 |
| Long gene name: |
glutaredoxin pseudogene 2 |
| Synonyms gene name: |
glutaredoxin (thioltransferase) pseudogene 2 |
| Locus: |
14q32, 11 |
| Discovery year: |
2002-12-19 |
| GenBank acession: |
AF358259 |
| Entrez gene record: |
171418 |
| Pubmed identfication: |
11702225 |