| Long name: |
ALEXA FLUOR 594 Conjugated, GLUD2 Polyclonal Antibody |
| Also known as: |
Anti-GLUD2 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GLUD2 |
| Specificity: |
This is a highly specific antibody against GLUD2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GLUD2 |
| Gene ID Number: |
2747 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Exisiting as homohexamers, GLUD1 catalyzes the oxidative deamination of glutamate to ?ketoglutarate and ammonia while GLUD2 is involved in the recycling of glutamate during neurotransmission, GLUD1 is critical for regulating amino acid induced insulin secretion and is allosterically activated by ADP and inhibited by GTP and ATP, GLUD1 may also be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate, GLUD2 is expressed in testis and retina, Mutations in the gene encoding GLUD1 causes hyperinsulinism-hyperammonemia syndrome (HHS), which is an inherited condition characterized by high insulin and ammonia levels in the blood, with lower levels found in brain, GLUD2 is both mitochondrial matrix enzymes belonging to the Glu/Leu/Phe/Val dehydrogenases family |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
GLUD2 |
| Short name: |
GLUD2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, GLUD2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4336 |
| Gene: |
GLUD2 |
More about : GLUD2 |
| Long gene name: |
glutamate dehydrogenase 2 |
| Synonyms gene: |
GLUDP1 |
| Synonyms gene name: |
glutamate dehydrogenase pseudogene 1 |
| Locus: |
Xq24 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
U08997 |
| Entrez gene record: |
2747 |
| Pubmed identfication: |
8207021 9109504 |
| RefSeq identity: |
NM_012084 |
| Havana BLAST/BLAT: |
OTTHUMG00000022320 |
| Locus Specific Databases: |
Mental Retardation database |