| Long name: |
FITC Conjugated, GGA3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GGA3 |
| Specificity: |
This is a highly specific antibody against GGA3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GGA3 |
| Gene ID number: |
23163 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ARF (ADP-ribosylation factor), ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, GGA1, GGAs have modular structures with an N-terminal VHS (VPS27, Hrs and STAM) domain followed by a GAT (GGA and Tom1) domain, Members of the GGA family, The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences, The human GGA3 gene maps to chromosome 17 and encodes a 723 amino acid protein that shares 46% sequence identity with GGA1 and 38% with GGA2, a connecting hinge segment and a C-terminal GAE (g-Adaptin ear) domain, and clathrin, are multi-domain proteins that bind mannose 6-phosphate receptors (MPRs), g-Adaptin ear-containing, GGA2 (also known as VEAR) and GGA3, The GGA family of proteins (Golgi-localized |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
KIAA0154 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GGA3 Conjugated |
| Short name: |
FITC Conjugated, GGA3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GGA3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17079 |
| Gene: |
GGA3 |
More about : GGA3 |
| Long gene name: |
ARF binding protein 3 , gamma adaptin ear containing, golgi associated |
| Synonyms gene name: |
ARF binding protein 3 , gamma adaptin ear containing, golgi-associated |
| Locus: |
17q25, 1 |
| Discovery year: |
2001-12-19 |
| GenBank acession: |
AF190864 |
| Entrez gene record: |
23163 |
| Pubmed identfication: |
10747089 10749927 |
| RefSeq identity: |
NM_138619 |
| Classification: |
ARF binding proteins , Golgi associated, gamma adaptin ear containing |
| Havana BLAST/BLAT: |
OTTHUMG00000179483 |