| Long name: |
Biotin Conjugated, PDE4D Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PDE4D |
| Specificity: |
This is a highly specific antibody against PDE4D |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human PDE4D |
| Gene ID number: |
5144 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
D2, D3, D4 and D5), In CNS all five PDE4D subtype variants are expressed in varying ratios and their activity is regulated in tandem with GPCRs stimulation, MAP kinases and Erk2 phosphorylation that results in rapid change in their enzymatic activities, One or more PDE4D subtype variants are ubiquitously present in all mammalian cells, Other regulatory mechanism involved protein protein interactions with cytoskeletal scaffolding proteins, PDE4D1/D2 mRNA levels rise in response to an increase in cAMP, Peripheral tissues also exhibit differential expression of PDE4D variants, Short term regulation of PDE4D variants involved PKA, Cyclic AMP-dependent phosphodiesterase type D (PDE4D) family is comprise of 5 variants (PDE4D1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PDE4D Conjugated |
| Short name: |
Conjugated, PDE4D Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, PDE4D (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8783 |
| Gene: |
PDE4D |
More about : PDE4D |
| Long gene name: |
phosphodiesterase 4D |
| Synonyms gene: |
DPDE3 |
| Synonyms gene name: |
cAMP-specific , cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E3) phosphodiesterase 4D, phosphodiesterase 4D |
| Synonyms name: |
phosphodiesterase E3 dunce homolog (Drosophila) |
| Locus: |
5q11, 1 , 2-q12 |
| Discovery year: |
1992-06-08 |
| Entrez gene record: |
5144 |
| Classification: |
Phosphodiesterases |
| Havana BLAST/BLAT: |
OTTHUMG00000162218 |