| Long name: |
FITC Conjugated, FMN1/Formin 1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FMN1/Formin 1 |
| Specificity: |
This is a highly specific antibody against FMN1/Formin 1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human FMN1/Formin 1 |
| Gene ID number: |
342184 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Deficiency mutations at the mammalian ld locus lead to profound developmental defects in limb and kidney formation, Formins co-localize with the actin cytoskeleton and can translocate into the cell cytosol and into the nucleus in an HGF-dependent manner, Formins play a crucial role in cytoskeletal reorganization by influencing Actin filament assembly, In mice, The human Formin 1 and 2 genes map to chromosome 15q13, Vertebrate nuclear formins can control polarizing activity in limb buds through establishment of a Sonic hedgehog/FGF-4 feedback loop, respectively, the limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of proteins known as formins, 3 and 1q43, The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
DKFZP686C2281 FLJ45135 MGC125288 MGC125289 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FMN1/Formin 1 Conjugated |
| Short name: |
FITC Conjugated, FMN1/Formin 1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, FMN1/Formin 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3768 |
| Gene: |
FMN1 |
More about : FMN1 |
| Long gene name: |
formin 1 |
| Synonyms gene: |
LD FMN |
| Synonyms gene name: |
formin (limb deformity) |
| Synonyms name: |
limb deformity protein |
| Locus: |
15q13, 3 |
| Discovery year: |
1990-03-12 |
| GenBank acession: |
AH002864 |
| Entrez gene record: |
342184 |
| Pubmed identfication: |
1673046 |
| RefSeq identity: |
NM_001103184 |
| Havana BLAST/BLAT: |
OTTHUMG00000172201 |