| Long name: |
FITC Conjugated, Reticulon 4 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Reticulon 4 |
| Specificity: |
Based on the location of the target sequence this antibody will recognize all isoforms(Nogo-A, Nogo-B, and Nogo-C), This is a highly specific antibody against Reticulon 4 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
1115-1160/1162 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from Mouse Reticulon 4 |
| Gene ID number: |
68585 |
| Swiss Prot: |
Q99P72 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, Involved in down-regulation of growth, It regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex, May inhibit BACE1 activity and amyloid precursor protein processing, Reticulon 4 regulates neurite fasciculation, The reticulon protein is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells, and as a facilitator of neurite branching, branching and extension in the developing nervous system, stabilization of wiring and restriction of plasticity in the adult CNS, Reticulons are associated with the endoplasmic reticulum |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
ASY, Foocen, Foocen-M, Foocen-S, NSP, Neurite outgrowth inhibitor, Neuroendocrine-specific protein, Nogo protein, Nogo-A, Nogo-B, Nogo-C, RTN 4A, RTN 4B, RTN 4C, RTN-x, RTN-xL, RTN-xS, RTN4-B2, Reticulon-5, Rtn-T, Rtn4, euroendocrine-specific protein C homolog, Reticulon-4 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Reticulon 4 Conjugated |
| Short name: |
FITC Conjugated, Reticulon 4 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Reticulon 4 (Antibody to) |
| Alternative technique: |
antibodies |