| Long name: |
TRRAP Primary Polyclonal Antibody |
| Also known as: |
TRRAP PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TRRAP |
| Specificity: |
This is a highly specific antibody against TRRAP |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRRAP |
| Gene ID number: |
8295 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
E2F-1 is thought to regulate c-Myc expression via interactions with the retinoblastoma protein (2), Expression of trans-activated mutant TRRAP inhibits the oncogenic transformation of both c-Myc and E2F-1, Overexpression of c-Myc in certain cell types induces noncycling cells to enter the cell cycle via a mechanism involving E2F-1 (1), TRRAP (for transformation/transcription domain-associated protein) interacts specifically with both c-Myc and E2F-1, TRRAP shares homology with the ATM/PI 3-kinase family, and it is highly conserved in evolution (4, suggesting that TRRAP is required for these oncogenic transcription factor pathways (3), 5), The transcription factors c-Myc and E2F are involved in regulating cell cycle progression |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FLJ10671, PAF 350/400, PAF 400, PAF350/400, PAF400, STAF 40, STAF40, TR AP, TRAP, TRRAP_HUMAN, Tra 1, Tra1, Tra1 homolog, Transactivation / transformation domain associated protein, Transactivation/transformation domain associated protein, Transformation/transcription domain associated protein, 350/400 kDa PCAF associated factor |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TRRAP |
| Short name: |
TRRAP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TRRAP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12347 |
| Gene: |
TRRAP |
More about : TRRAP |
| Long gene name: |
transformation/transcription domain associated protein |
| Synonyms gene name: |
transformation/transcription domain-associated protein |
| Synonyms: |
TR-AP PAF400 Tra1 |
| Locus: |
7q22, 1 |
| Discovery year: |
1998-10-06 |
| GenBank acession: |
AF076974 |
| Entrez gene record: |
8295 |
| Pubmed identfication: |
9708738 9885574 |
| RefSeq identity: |
NM_003496 |
| Classification: |
SAGA complex |
| Havana BLAST/BLAT: |
OTTHUMG00000150403 |