| Long name: |
eRF1 Primary Polyclonal Antibody |
| Also known as: |
eRF1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
eRF1 |
| Specificity: |
This is a highly specific antibody against eRF1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human eRF1 |
| Gene ID number: |
2107 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
GTP and the ribosome, In eukaryotes, Termination of protein synthesis takes place when the ribosomal A site is occupied simultaneously by one of three stop codons and by a class 1 translation termination factor, The gene encoding human eRF1 maps to chromosome 5q31, This complex performs a dual role, a protein that promotes hydrolysis of the last peptidyl-tRNA on the ribosome, and, eRF1 activity is stimulated by the association with the GTP-binding protein eRF3, eRF1 contains a highly conserved Asn-Ile-Lys-Ser (NIKS) tetrapeptide, eRF1 forms a quaternary complex with eRF3, elongation and termination, in the â, in the â, this termination factor is the eukaryotic release factor 1 (eRF1), where, which is essential for the interaction of eRF1 with the ribosome, â, â, &euro, &euro, &euro, &euro, &oelig, &oelig, 2, GDP state, GTP state, Translation is carried out by the ribosome and several associated protein factors through three consecutive steps: initiation, it controls the positioning of eRF1 toward the stop codon and peptidyl-tRNA, it promotes the release of the eRFs from the ribosome |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
D5S1995, ERF, ERF1_HUMAN, ETF1, Eukaryotic peptide chain release factor subunit 1, Eukaryotic release factor 1, Eukaryotic translation termination factor 1, MGC111066, Polypeptide chain release factor 1, Protein Cl1, RF1, SUP45L1, Sup45 yeast omnipotent suppressor 45 homolog like 1, TB3 1, TB3-1, eRF1, Cl1 protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
eRF1 |
| Short name: |
eRF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
eRF1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3477 |
| Gene: |
ETF1 |
More about : ETF1 |
| Long gene name: |
eukaryotic translation termination factor 1 |
| Synonyms gene: |
SUP45L1 ERF1 ERF |
| Synonyms: |
eRF1 TB3-1 RF1 |
| Synonyms name: |
sup45 (yeast omnipotent suppressor 45) homolog-like 1 polypeptide chain release factor 1 |
| Locus: |
5q31, 2 |
| Discovery year: |
1991-06-13 |
| GenBank acession: |
AF095901 |
| Entrez gene record: |
2107 |
| Pubmed identfication: |
1546371 7990965 |
| RefSeq identity: |
NM_004730 |
| Havana BLAST/BLAT: |
OTTHUMG00000129199 |