HER4 (Tyr1258) Antibody, Biotin Conjugated

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Catalog number: bs-13093R-Biotin
Price: 368 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: HER4 (Tyr1258) Antibody, Biotin Conjugated
Quantity: 0.1ml
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More details :

Long name: Biotin Conjugated, HER4 (Tyr1258) Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Biotinylated
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: HER4 Tyr1258
Specificity: This is a highly specific antibody against HER4 Tyr1258
Modification: Phosphorylation
Modification site: Tyr1258
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic phosphopeptide derived from human HER4 around the phosphorylation site of Tyr1258 [PD(p-Y)LQ ]
Gene ID number: 2066
Tested applications: IHC-P, WB
Recommended dilutions: IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity: Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Alternatively spliced variants which encode different protein isoforms have been described, It encodes a single-pass type I membrane protein with multiple cysteine rich domains, Jul 2008], Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment, Mutations in this gene have been associated with cancer, The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation, [provided by RefSeq, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif, a transmembrane domain, a tyrosine kinase domain, however, not all variants have been fully characterized, This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms: ALS19 HER4
Properties: Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target: HER4 (Tyr1258) Conjugated
Short name: Conjugated, HER4 (Tyr1258) Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: Biotin
Alternative name: biotinilated coupled, HER4 (Tyr1258) (Antibody to)
Alternative technique: antibodies
Identity: 3432
Gene: ERBB4 | More about : ERBB4
Long gene name: erb-b2 receptor tyrosine kinase 4
Synonyms gene name: v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
Synonyms name: human epidermal growth factor receptor 4
Locus: 2q34
Discovery year: 1995-09-07
GenBank acession: L07868
Entrez gene record: 2066
Pubmed identfication: 7700649 17018285
RefSeq identity: NM_001042599
Classification: Erb-b2 receptor tyrosine kinases
Havana BLAST/BLAT: OTTHUMG00000133012

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