| Long name: |
ALEXA FLUOR 647 Conjugated, SFRP1 Polyclonal Antibody |
| Also known as: |
Anti-SFRP1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SFRP1 |
| Specificity: |
This is a highly specific antibody against SFRP1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
265-310/314 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SFRP1 |
| Gene ID Number: |
6422 |
| Swiss Prot: |
Q8N474 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Has antiproliferative effects on vascular cells, In kidney development, In vascular cell cycle, Inhibits WNT1/WNT4-mediated TCF-dependent transcription, SFRP1 decreases intracellular beta-catenin levels (By similarity), They have a role in regulating cell growth and differentiation in specific cell types, an angiogenic response, and can induce, delays the G1 phase and entry into the S phase (By similarity), in vitro and in vivo, in vivo, inhibits tubule formation and bud growth in metanephroi (By similarity), Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
SARP2 FRP FRP-1 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the SFRP1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
SFRP1 |
| Short name: |
SFRP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, secreted frizzled-related protein 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046546 and development of primary male sexual characteristics and biological process this GO :0046676 and negative regulation of insulin secretion and biological process this GO :0046851 and negative regulation of bone remodeling and biological process this GO :0048147 and negative regulation of fibroblast proliferation and biological process this GO :0048546 and digestive tract morphogenesis and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0050732 and negative regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051496 and positive regulation of stress fiber assembly and biological process this GO :0051894 and positive regulation of focal adhesion assembly and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060071 and Wnt signaling pathway, Extracellular, FRP and FRP-1 and FRP1 and FrzA and SARP2, SFRP1 and IDBG-18868 and ENSG00000104332 and 6422, Sfrp1 and IDBG-142213 and ENSMUSG00000031548 and 20377, Wnt-activated receptor activity, planar cell polarity pathway and biological process this GO :0060218 and hematopoietic stem cell differentiation and biological process this GO :0060346 and bone trabecula formation and biological process this GO :0060527 and prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis and biological process this GO :0060687 and regulation of branching involved in prostate gland morphogenesis and biological process this GO :0060766 and negative regulation of androgen receptor signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071305 and cellular response to vitamin D and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071380 and cellular response to prostaglandin E stimulus and biological process this GO :0071391 and cellular response to estrogen stimulus and biological process this GO :0071392 and cellular response to estradiol stimulus and biological process this GO :0071456 and cellular response to hypoxia and biological process this GO :0071481 and cellular response to X-ray and biological process this GO :0071504 and cellular response to heparin and biological process this GO :0071560 and cellular response to transforming growth factor beta stimulus and biological process this GO :0071773 and cellular response to BMP stimulus and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0090175 and regulation of establishment of planar polarity and biological process this GO :0090179 and planar cell polarity pathway involved in neural tube closure and biological process this GO :0090244 and Wnt signaling pathway involved in somitogenesis and biological process this GO :0090246 and convergent extension involved in somitogenesis and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process this GO :1902043 and positive regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000041 and negative regulation of planar cell polarity pathway involved in axis elongation and biological process this GO :2000052 and positive regulation of non-canonical Wnt signaling pathway and biological process this GO :2000054 and negative regulation of Wnt receptor signaling pathway involved in dorsal/ventral axis specification and biological process this GO :2000080 and negative regulation of canonical Wnt receptor signaling pathway involved in controlling type B pancreatic cell proliferation and biological process this GO :2000270 and negative regulation of fibroblast apoptotic process and biological process this GO :2000271 and positive regulation of fibroblast apoptotic process and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0001649 and osteoblast differentiation and biological process this GO :0001657 and ureteric bud development and biological process this GO :0001756 and somitogenesis and biological process this GO :0001843 and neural tube closure and biological process this GO :0001944 and vasculature development and biological process this GO :0001954 and positive regulation of cell-matrix adhesion and biological process this GO :0002244 and hematopoietic progenitor cell differentiation and biological process this GO :0004197 and cysteine-type endopeptidase activity and molecular function this GO :0005109 and frizzled binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006508 and proteolysis and biological process this GO :0007420 and brain development and biological process this GO :0008144 and drug binding and molecular function this GO :0008201 and heparin binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0008406 and this GO nad development and biological process this GO :0008584 and male this GO nad development and biological process this GO :0008585 and female this GO nad development and biological process this GO :0009267 and cellular response to starvation and biological process this GO :0009950 and dorsal/ventral axis specification and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0009986 and cell surface and cellular component this GO :0010564 and regulation of cell cycle process and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0010719 and negative regulation of epithelial to mesenchymal transition and biological process this GO :0014034 and neural crest cell fate commitment and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0017147 and Wnt-protein binding and molecular function this GO :0021915 and neural tube development and biological process this GO :0022601 and menstrual cycle phase and biological process this GO :0030097 and hemopoiesis and biological process this GO :0030165 and PDZ domain binding and molecular function this GO :0030177 and positive regulation of Wnt signaling pathway and biological process this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030279 and negative regulation of ossification and biological process this GO :0030307 and positive regulation of cell growth and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0030514 and negative regulation of BMP signaling pathway and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0032855 and positive regulation of Rac GTPase activity and biological process this GO :0033689 and negative regulation of osteoblast proliferation and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0042493 and response to drug and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042813 and Wnt-activated receptor activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043508 and negative regulation of JUN kinase activity and biological process this GO :0044344 and cellular response to fibroblast growth factor stimulus and biological process this GO :0044345 and stromal-epithelial cell signaling involved in prostate gland development and biological process this GO :0045578 and negative regulation of B cell differentiation and biological process this GO :0045600 and positive regulation of fat cell differentiation and biological process this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0045671 and negative regulation of osteoclast differentiation and biological process this GO :0045765 and regulation of angiogenesis and biological process this GO :0045880 and positive regulation of smoothened signaling pathway and biological process this GO :0045892 and negative regulation of transcription, this GO :0004197 : cysteine-type endopeptidase activity, this GO :0004197 : cysteine-type endopeptidase activity and also this GO :0005109 : frizzled binding and also this GO :0005515 : protein binding and also this GO :0008144 : drug binding and also this GO :0008201 : heparin binding and also this GO :0017147 : Wnt-protein binding and also this GO :0030165 : PDZ domain binding and also this GO :0042802 : identical protein binding and also this GO :0042813 : Wnt-activated receptor activity, this GO :0005109 : frizzled binding, this GO :0005515 : protein binding, this GO :0008144 : drug binding, this GO :0008201 : heparin binding, this GO :0017147 : Wnt-protein binding, this GO :0030165 : PDZ domain binding, this GO :0042802 : identical protein binding, this GO :0042813 : Wnt-activated receptor activity, 85254 and IDBG-629640 and ENSBTAG00000027625 and 282068, secreted frizzled-related protein 1 |
| Identity: |
10776 |
| Gene: |
SFRP1 |
More about : SFRP1 |
| Long gene name: |
secreted frizzled related protein 1 |
| Locus: |
8p11, 21 |
| Discovery year: |
1998-07-15 |
| GenBank acession: |
AF017987 |
| Entrez gene record: |
6422 |
| Pubmed identfication: |
9391078 9192640 |
| RefSeq identity: |
NM_003012 |
| Classification: |
Secreted frizzled-related proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000164074 |