| Long name: |
DRIP130/CRSP130 Primary Polyclonal Antibody |
| Also known as: |
DRIP130/CRSP130 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DRIP130/CRSP130 |
| Specificity: |
This is a highly specific antibody against DRIP130/CRSP130 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DRIP130/CRSP130 |
| Gene ID number: |
9439 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex that consists of nine distinct subunits (3), CRSP subunits also associate with larger multimeric coactivaor complexes, CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, Several members of the CRSP family share sequence similarity with multiple components of the yeast transcriptional mediator proteins, These complexes include CRSP (for cofactor required for Sp1 activation), a polymerase II-interacting complex that represses activated transcription (6, and CRSP70, and with NAT, for transcriptional activation by Sp1 (2), in conjunction with TAFIIs, including ARC/DRI, including CRSP150, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1), which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, which is related to yeast Rgr1, which is required, which is similar to the elongation factor TFIIS (4), while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins (2, 5), 7), In mammalian cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
133 kDa transcriptional co activator, ARC 130, ARC130, Activator recruited cofactor 130 kDa component, Activator-recruited cofactor 130 kDa component, CRSP 130, CRSP 130 kD subunit, CRSP 133, CRSP 3, CRSP complex subunit 3, CRSP130, CRSP133, CRSP3, CRSP3 protein, Cofactor required for Sp1 transcriptional activation subunit 3, Cofactor required for Sp1 transcriptional activation subunit 3 130kDa, Cofactor required for Sp1 transcriptional activation subunit 3 130kDa mediator, DKFZp434H0117, DRIP 130, DRIP130, KIAA1216, MED 23, MED23, MED23_HUMAN, Mediator complex subunit 23, Mediator of RNA polymerase II transcription subunit 23, Protein sur-2 homolog, SUR 2, SUR2, Transcriptional co activator CRSP 130, Transcriptional co activator CRSP130, Transcriptional coactivator CRSP130, Vitamin D3 receptor interacting protein, Vitamin D3 receptor interacting protein complex 130 kDa component, Vitamin D3 receptor-interacting protein complex 130 kDa component, hSur-2, 130 kDa transcriptional co activator |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DRIP130/CRSP130 |
| Short name: |
DRIP130/CRSP130 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DRIP130/CRSP130 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2372 |
| Gene: |
MED23 |
More about : MED23 |
| Long gene name: |
mediator complex subunit 23 |
| Synonyms gene: |
CRSP3 |
| Synonyms gene name: |
130kDa , cofactor required for Sp1 transcriptional activation, subunit 3 |
| Synonyms: |
CRSP130 DRIP130 Sur2 |
| Locus: |
6q23, 2 |
| Discovery year: |
1999-07-21 |
| GenBank acession: |
AF104255 |
| Entrez gene record: |
9439 |
| Pubmed identfication: |
9989412 |
| Classification: |
Mediator complex |
| Havana BLAST/BLAT: |
OTTHUMG00000015565 |