| Long name: |
Biotin Conjugated, DGAT2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DGAT2 |
| Specificity: |
This is a highly specific antibody against DGAT2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human DGAT2 |
| Gene ID number: |
84649 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acyl-coenzyme A:diacylglycerol acyltransferase, DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates, DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, DGAT2, DGAT2 is expressed primarily in liver and white adipose tissue, adipose tissue form-ation and lactation, also known as DGAT1 and ARGP1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides, lipoprotein assembly, such as intestinal fat absorption, which has no homology to DGAT1, which suggests that it plays an important role in mammalian triglyceride metabolism, Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DGAT2 Conjugated |
| Short name: |
Conjugated, DGAT2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, DGAT2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16940 |
| Gene: |
DGAT2 |
More about : DGAT2 |
| Long gene name: |
diacylglycerol O-acyltransferase 2 |
| Synonyms gene name: |
diacylglycerol O-acyltransferase homolog 2 (mouse) |
| Locus: |
11q13, 5 |
| Discovery year: |
2001-11-19 |
| Entrez gene record: |
84649 |
| Pubmed identfication: |
11481335 14970677 |
| RefSeq identity: |
NM_032564 |
| Classification: |
Diacylglycerol O-acyltransferase 2 family |
| Havana BLAST/BLAT: |
OTTHUMG00000165338 |