| Long name: |
ALEXA FLUOR 488 Conjugated, DGAT2 Polyclonal Antibody |
| Also known as: |
Anti-DGAT2 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DGAT2 |
| Specificity: |
This is a highly specific antibody against DGAT2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DGAT2 |
| Gene ID Number: |
84649 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acyl-coenzyme A:diacylglycerol acyltransferase, DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates, DGAT1 plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism, DGAT2, DGAT2 is expressed primarily in liver and white adipose tissue, adipose tissue form-ation and lactation, also known as DGAT1 and ARGP1, differs from DGAT1 in that its activity has been shown to be inhibited by MgCl in an in vitro assay, is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides, lipoprotein assembly, such as intestinal fat absorption, which has no homology to DGAT1, which suggests that it plays an important role in mammalian triglyceride metabolism, Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the DGAT2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
DGAT2 |
| Short name: |
DGAT2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, DGAT2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16940 |
| Gene: |
DGAT2 |
More about : DGAT2 |
| Long gene name: |
diacylglycerol O-acyltransferase 2 |
| Synonyms gene name: |
diacylglycerol O-acyltransferase homolog 2 (mouse) |
| Locus: |
11q13, 5 |
| Discovery year: |
2001-11-19 |
| Entrez gene record: |
84649 |
| Pubmed identfication: |
11481335 14970677 |
| RefSeq identity: |
NM_032564 |
| Classification: |
Diacylglycerol O-acyltransferase 2 family |
| Havana BLAST/BLAT: |
OTTHUMG00000165338 |