| Catalog number: | bs-12971R-A594 |
|---|---|
| Price: | 332 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | alpha B Crystallin (Ser53) Antibody, ALEXA FLUOR 594 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 594 Conjugated, alpha B Crystallin (Ser53) Antibody |
|---|---|
| Also known as: | Anti-alpha B Crystallin Ser53 PAb ALEXA FLUOR 594 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 594, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | alpha B Crystallin Ser53 |
| Specificity: | This is a highly specific antibody against alpha B Crystallin Ser53 |
| Modification: | Phosphorylation |
| Modification Site: | Ser53 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic phosphopeptide derived from human alpha B Crystallin around the phosphorylation site of Ser53 |
| Gene ID Number: | 1410 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Alpha and beta families are further divided into acidic and basic groups, Alpha crystallins are composed of two gene products: alpha-A and alpha-B, Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family, Alpha-A and alpha-B gene products are differentially expressed, Elevated expression of alpha-B crystallin occurs in many neurological diseases, Jul 2008], Mammalian lens crystallins are divided into alpha, Post-translational modifications decrease the ability to chaperone, Seven protein regions exist in crystallins: four homologous motifs, Since lens central fiber cells lose their nuclei during development, The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens, These heterogeneous aggregates consist of 30-40 subunits, They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture, [provided by RefSeq, a connecting peptide, a missense mutation cosegregated in a family with a desmin-related myopathy, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs, and N- and C-terminal extensions, and gamma families, and ubiquitous, beta, beta and gamma crystallins are also considered as a superfamily, for acidic and basic, instead they hold them in large soluble aggregates, making them extremely stable proteins, or enzyme, respectively, respectively, the alpha-A and alpha-B subunits have a 3:1 ratio, these crystallins are made and then retained throughout life, Crystallins are separated into two classes: taxon-specific |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 590nm/617nm |
| Synonyms: | Alpha(B)-crystallin, CRYA2, CRYAB, Heat shock protein beta-5, HspB5, Renal carcinoma antigen NY-REN-27, Rosenthal fiber component, Alpha-crystallin B chain |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: | Alexa conjugate 1 |
| Gene target: | alpha B Crystallin (Ser53) |
| Short name: | alpha B Crystallin (Ser53) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 594 |
| Alternative name: | ALEXA FLUOR 594, a B Crystallin (Ser53) (Antibody to) |
| Alternative technique: | antibodies |
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