| Long name: |
Aromatase Primary Polyclonal Antibody |
| Also known as: |
Aromatase PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Aromatase |
| Specificity: |
This is a highly specific antibody against Aromatase |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
65-120/503 |
| Subcellular location: |
Cell membrane |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Aromatase |
| Gene ID number: |
1588 |
| Swiss Prot: |
P11511 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Belongs to the cytochrome P450 family, Mutations in this gene can result in either increased or decreased aromatase activity, The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, The gene expresses two transcript variants, This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, steroids and other lipids, the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation, three successive hydroxylations of the A ring of androgens, This gene encodes a member of the cytochrome P450 superfamily of enzymes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ARO1, Aromatase, CPV1, CYAR, CYP19, CYP19A1, CYPXIX, Cytochrome P-45AROM, Cytochrome P45 19A1, Estrogen synthase, P-45AROM, ARO |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Aromatase |
| Short name: |
Aromatase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Aromatase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2594 |
| Gene: |
CYP19A1 |
More about : CYP19A1 |
| Long gene name: |
cytochrome P450 family 19 subfamily A member 1 |
| Synonyms gene: |
CYP19 |
| Synonyms gene name: |
cytochrome P450, family 19, polypeptide 1 , subfamily A, subfamily XIX (aromatization of androgens) cytochrome P450 |
| Synonyms: |
ARO P-450AROM CPV1 ARO1 CYAR aromatase |
| Locus: |
15q21, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
D14473 |
| Entrez gene record: |
1588 |
| Pubmed identfication: |
8477708 |
| Classification: |
Cytochrome P450 family 19 |
| Havana BLAST/BLAT: |
OTTHUMG00000131747 |
| Locus Specific Databases: |
Human Cytochrome P450 (CYP) Allele Nomenclature Committee |