| Catalog number: | bs-12883R-Cy3 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | BRAF35 Antibody, Cy3 Conjugated |
| Quantity: | 0.1ml |
| Related search: |
| Long name: | Cy3 Conjugated, BRAF35 Polyclonal Antibody |
|---|---|
| Category: | Conjugated Primary Antibodies |
| Conjugation: | cy3 conjugation kit |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | BRAF35 |
| Specificity: | This is a highly specific antibody against BRAF35 |
| Modification: | Unmodified |
| Modification site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic peptide derived from human BRAF35 |
| Gene ID number: | 10362 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Crossreactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: | A second breast cancer susceptibility gene, BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns, BRCA2, BRCA2 does not confer a substantially elevated risk of ovarian cancer, Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer, The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation, The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain, also confers a high incidence of breast cancer, but unlike BRCA1, located on chromosome 13q12-13, which associates with condensed chromatin during histone H3 phosphorylation, The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: | 512, 550nm/570, 615nm |
| Synonyms: | SOXL HMGX2 BRAF35 SMARCE1r BRAF25 HMGXB2 |
| Properties: | 1 of the BRAF35 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | BRAF35 Conjugated |
| Short name: | Conjugated, BRAF35 Antibody |
| Technique: | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: | Cy3 |
| Alternative name: | cyanine 3 coupled, BRAF35 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 5002 |
| Gene: | HMG20B | More about : HMG20B |
| Long gene name: | high mobility group 20B |
| Synonyms gene name: | high-mobility group 20B |
| Synonyms name: | HMG box domain containing 2 |
| Locus: | 19p13, 3 |
| Discovery year: | 1999-06-11 |
| GenBank acession: | BC003505 |
| Entrez gene record: | 10362 |
| Pubmed identfication: | 10773667 |
| RefSeq identity: | NM_006339 |
| Classification: | Non-canonical high mobility group |
| Havana BLAST/BLAT: | OTTHUMG00000150437 |
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