| Long name: |
ALEXA FLUOR 350 Conjugated, BRAF35 Polyclonal Antibody |
| Also known as: |
Anti-BRAF35 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
BRAF35 |
| Specificity: |
This is a highly specific antibody against BRAF35 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BRAF35 |
| Gene ID Number: |
10362 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
A second breast cancer susceptibility gene, BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns, BRCA2, BRCA2 does not confer a substantially elevated risk of ovarian cancer, Mutations within this gene account for approximately 45% of families with high incidence of breast cancer and at least 80% of families with increased incidence of both early-onset breast cancer and ovarian cancer, The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation, The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain, also confers a high incidence of breast cancer, but unlike BRCA1, located on chromosome 13q12-13, which associates with condensed chromatin during histone H3 phosphorylation, The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
SOXL HMGX2 BRAF35 SMARCE1r BRAF25 HMGXB2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
BRAF35 |
| Short name: |
BRAF35 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, BRAF35 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5002 |
| Gene: |
HMG20B |
More about : HMG20B |
| Long gene name: |
high mobility group 20B |
| Synonyms gene name: |
high-mobility group 20B |
| Synonyms name: |
HMG box domain containing 2 |
| Locus: |
19p13, 3 |
| Discovery year: |
1999-06-11 |
| GenBank acession: |
BC003505 |
| Entrez gene record: |
10362 |
| Pubmed identfication: |
10773667 |
| RefSeq identity: |
NM_006339 |
| Classification: |
Non-canonical high mobility group |
| Havana BLAST/BLAT: |
OTTHUMG00000150437 |