| Long name: |
Cy7 Conjugated, BLM/Blooms Syndrome Protein Blm Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
BLM/Blooms Syndrome Protein Blm |
| Specificity: |
This is a highly specific antibody against BLM/Blooms Syndrome Protein Blm |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human BLM/Blooms Syndrome Protein Blm |
| Gene ID number: |
641 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
BLM, BLM has been shown to unwind G4 DNA, BLM is known to be translocated to the nucleus, Mutations in the yeast SGS1, One characteristic of Bloomâ, The gene responsible for Bloomâ, a homolog of BLM, and a failure of this function is thought to be responsible for the increased rate of SCE, are known to cause mitotic hyperrecombination similiar to that observed in Bloomâ, coli and is mutated in most Bloomâ, encodes a protein homologous to the RecQ helicase of E, immunodeficiency and a predisposition to various cancers, sun sensitivity, where its ATPase activity is stimulated by both single- and double-stranded DNA, &euro, &euro, &euro, &euro, &euro, &trade, &trade, &trade, &trade, &trade, Bloomâ, s cells, s syndrome, s syndrome is an autosomal recessive disorder characterized by pre- and post-natal growth deficiencies, s syndrome is an increased frequency of sister chromatid exchange (SCE), s syndrome patients |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
BS RECQL3 RECQ2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
BLM/Blooms Syndrome Protein Blm Conjugated |
| Short name: |
Conjugated, BLM/Blooms Syndrome Protein Blm Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
RecQ helicase-like (Antibody to), RecQ helicase-like/Blooms Syndrome Protein Bloom syndrome, cyanine 7 coupled, Bloom syndrome |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BLM and IDBG-30365 and ENSG00000197299 and 641, BLM and IDBG-629490 and ENSBTAG00000020301 and 534148, BS and RECQ2 and RECQL2 and RECQL3, Blm and IDBG-195418 and ENSMUSG00000030528 and 12144, DNA-templated and biological process this GO :0045910 and negative regulation of DNA recombination and biological process this GO :0045950 and negative regulation of mitotic recombination and biological process this GO :0046632 and alpha-beta T cell differentiation and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0048478 and replication fork protection and biological process this GO :0051098 and regulation of binding and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0051276 and chromosome organization and biological process this GO :0051782 and negative regulation of cell division and biological process this GO :0051880 and G-quadruplex DNA binding and molecular function this GO :0070244 and negative regulation of thymocyte apoptotic process and biological process this GO :0071479 and cellular response to ionizing radiation and biological process this GO :0072711 and cellular response to hydroxyurea and biological process this GO :0072757 and cellular response to camptothecin and biological process, RecQ helicase-like, acting on acid anhydrides, acting on acid anhydrides, acting on acid anhydrides, hydrolase activity, in phosphorus-containing anhydrides, in phosphorus-containing anhydrides and also this GO :0016887 : ATPase activity and also this GO :0036310 : annealing helicase activity and also this GO :0043140 : ATP-dependent 3'-5' DNA helicase activity and also this GO :0051880 : G-quadruplex DNA binding, in phosphorus-containing anhydrides and molecular function this GO :0016887 and ATPase activity and molecular function this GO :0031297 and replication fork processing and biological process this GO :0031572 and G2 DNA damage checkpoint and biological process this GO :0032508 and DNA duplex unwinding and biological process this GO :0036310 and annealing helicase activity and molecular function this GO :0043140 and ATP-dependent 3'-5' DNA helicase activity and molecular function this GO :0044237 and cellular metabolic process and biological process this GO :0045120 and pronucleus and cellular component this GO :0045893 and positive regulation of transcription, nuclei, telomeric region and cellular component this GO :0000800 and lateral element and cellular component this GO :0001673 and male germ cell nucleus and cellular component this GO :0002039 and p53 binding and molecular function this GO :0003676 and nucleic acid binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003697 and single-stranded DNA binding and molecular function this GO :0003824 and catalytic activity and molecular function this GO :0004003 and ATP-dependent DNA helicase activity and molecular function this GO :0004386 and helicase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005657 and replication fork and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006260 and DNA replication and biological process this GO :0006281 and DNA repair and biological process this GO :0006310 and DNA recombination and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0008026 and ATP-dependent helicase activity and molecular function this GO :0009378 and four-way junction helicase activity and molecular function this GO :0010165 and response to X-ray and biological process this GO :0016363 and nuclear matrix and cellular component this GO :0016605 and PML body and cellular component this GO :0016818 and hydrolase activity, this GO :0000079 and regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0000085 and mitotic G2 phase and biological process this GO :0000166 and nucleotide binding and molecular function this GO :0000228 and nuclear chromosome and cellular component this GO :0000405 and bubble DNA binding and molecular function this GO :0000723 and telomere maintenance and biological process this GO :0000724 and double-strand break repair via homolo this GO us recombination and biological process this GO :0000729 and DNA double-strand break processing and biological process this GO :0000733 and DNA strand renaturation and biological process this GO :0000781 and chromosome, this GO :0000166 : nucleotide binding, this GO :0000166 : nucleotide binding and also this GO :0000405 : bubble DNA binding and also this GO :0002039 : p53 binding and also this GO :0003676 : nucleic acid binding and also this GO :0003677 : DNA binding and also this GO :0003697 : single-stranded DNA binding and also this GO :0003824 : catalytic activity and also this GO :0004003 : ATP-dependent DNA helicase activity and also this GO :0004386 : helicase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0008026 : ATP-dependent helicase activity and also this GO :0009378 : four-way junction helicase activity and also this GO :0016818 : hydrolase activity, this GO :0000405 : bubble DNA binding, this GO :0002039 : p53 binding, this GO :0003676 : nucleic acid binding, this GO :0003677 : DNA binding, this GO :0003697 : single-stranded DNA binding, this GO :0003824 : catalytic activity, this GO :0004003 : ATP-dependent DNA helicase activity, this GO :0004386 : helicase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0008026 : ATP-dependent helicase activity, this GO :0009378 : four-way junction helicase activity, this GO :0016818 : hydrolase activity, this GO :0016887 : ATPase activity, this GO :0036310 : annealing helicase activity, this GO :0043140 : ATP-dependent 3'-5' DNA helicase activity, this GO :0051880 : G-quadruplex DNA binding, Bloom syndrome |
| Identity: |
1058 |
| Gene: |
BLM |
More about : BLM |
| Long gene name: |
Bloom syndrome RecQ like helicase |
| Synonyms gene name: |
Bloom syndrome |
| Locus: |
15q26, 1 |
| Discovery year: |
1992-11-06 |
| GenBank acession: |
U39817 |
| Entrez gene record: |
641 |
| Pubmed identfication: |
9388193 |
| Classification: |
RecQ like helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000149834 |
| Locus Specific Databases: |
BLMbase: Mutation registry for Bloom Syndrome LRG_20 |