| Long name: |
DAP12 Primary Polyclonal Antibody |
| Also known as: |
DAP12 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DAP12 |
| Specificity: |
This is a highly specific antibody against DAP12 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DAP12 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Its putative receptor, Mar 2010], Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene, Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element, This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, [provided by RefSeq, also causes PLOSL, also known as Nasu-Hakola disease, and inflammation, bone modeling, brain myelination, triggering receptor expressed on myeloid cells 2 (TREM2), This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DAP12, DNAX activation protein 12, DNAX-activation protein 12, KAR-associated protein, KARAP, Killer activating receptor associated protein, Killer-activating receptor-associated protein, PLOSL, TYOBP_HUMAN, TYRO protein tyrosine kinase binding protein, TYRO protein tyrosine kinase-binding protein, TYROBP, DAP 12 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DAP12 |
| Short name: |
DAP12 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DAP12 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12449 |
| Gene: |
TYROBP |
More about : TYROBP |
| Long gene name: |
TYRO protein tyrosine kinase binding protein |
| Synonyms gene: |
PLOSL |
| Synonyms: |
DAP12 PLO-SL KARAP |
| Synonyms name: |
killer activating receptor associated protein DNAX-activation protein 12 |
| Locus: |
19q13, 12 |
| Discovery year: |
1998-06-25 |
| GenBank acession: |
AF019563 |
| Entrez gene record: |
7305 |
| Pubmed identfication: |
9490415 10888890 |
| Havana BLAST/BLAT: |
OTTHUMG00000181739 |
| Locus Specific Databases: |
LRG_607 |