| Long name: |
Cy5 Conjugated, Bcl2 (Ser87) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Bcl2 Ser87 |
| Specificity: |
This is a highly specific antibody against Bcl2 Ser87 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser87 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Bcl2 around the phosphorylation site of Ser87 |
| Gene ID number: |
596 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Also interacts with APAF1, BAD, BAK and BclX(L), BBC3, BCL2 inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF1), BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells, BCL2L1 and BNIPL, Constitutive expression of BCL2, Heterodimerization with BAX requires intact BH1 and BH2 domains, It appears to function in a feedback loop system with caspases, It can form homodimers, It regulates cell death by controlling the mitochondrial membrane permeability, RAF1, TP53BP2, Two transcript variants (alpha and beta) produced by alternate splicing, and heterodimers with BAX, and is necessary for anti-apoptotic activity, differ in their C-terminal ends, is thought to be the cause of follicular lymphoma, such as in the case of translocation of BCL2 to Ig heavy chain locus, BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
2, AW986256, Apoptosis regulator Bcl 2, Apoptosis regulator Bcl-2, Apoptosis regulator Bcl2, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, B cell lymphoma 2, B-cell, BCL2 protein, BCL2_HUMAN, Bcl 2, Bcl-2, Bcl2, Bcl2 phospho Ser87, C430015F12Rik, D630044D05Rik, D830018M01Rik, Leukemia/lymphoma, Oncogene B-cell leukemia 2, p-Bcl2 Ser87, p-Bcl2 phospho S87, Bcl2 phospho S87 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Bcl2 (Ser87) Conjugated |
| Short name: |
Conjugated, Bcl2 (Ser87) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, B-cell CLL/lymphoma 2 (Ser87) (Antibody to) |
| Alternative technique: |
antibodies |