| Long name: |
Bacillus anthracis lethal factor Antibody |
| Also known as: |
Bacillus anthracis lethal factor Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Bacillus anthracis lethal factor |
| Specificity: |
This is a highly specific antibody against Bacillus anthracis lethal factor |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from Bacillus anthracis lethal factor |
| Gene ID number: |
1158731 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Others |
| Cross reactive species details: |
Anthrax LF (Lethal Factor) produced by Bacillus anthracis |
| Background of the target antigen: |
Cleavage invariably occurs within the N terminal proline rich region preceding the kinase domain, EF &, LF is not toxic by itself, LF then cleaves the N terminal of most dual specificity mitogen activated protein kinase kinases (MAPKKs or MAP2Ks) (except for MAP2K5), Once inside the cell, PA) composing the anthrax toxin produced by Bacillus anthracis, The proteasome may mediate a toxic process initiated by LF in the cell cytosol involving degradation of unidentified molecules that are essential for macrophage homeostasis, There may be other cytosolic targets of LF involved in cytotoxicity, This is an early step in LF intoxication, a bacteria which can infect many mammalian species and that may be fatal, but it is downstream of the cleavage by LF of MEK1 or other putative substrates, but when associated with Protective Antigen (PA), can then gain entry to cells, thus disrupting a sequence involved in directing specific protein protein interactions necessary for the assembly of signaling complexes, The protease enzyme Lethal Factor (LF) is one of the three proteins (LF |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Anthrax LF, Anthrax lethal toxin endopeptidase component, LEF_BACAN, LF, Lef, bacillus anthracis lethal factor, Anthrax lethal factor |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Description: |
Anthrax has a very high toxin level and is used in Biologic warfare, Aplha, Complex subunit associated factors are involved in hybridoma growth, Eosinohils, However 1 is a harmless product, NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation, Bacillus Anthracis and Cereus are the most known Bacilli |
| Gene target: |
Bacillus anthracis lethal factor |
| Short name: |
Bacillus anthracis lethal factor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Bacillus anthracis lethal factor (Antibody to) |
| Alternative technique: |
antibodies |