| Long name: |
ATM (Ser794) Primary Polyclonal Antibody |
| Also known as: |
ATM (Ser794) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ATM Ser794 |
| Specificity: |
This is a highly specific antibody against ATM Ser794 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser794 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human ATM around the phosphorylation site of Ser794 |
| Gene ID number: |
472 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ATM belongs to a novel family of proteins associated with cell cycle regulation, The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases), and response to DNA damage repair (DNA damage caused by such things as ionizing irradiation activates ATM kinase), apoptosis, ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AT complementation group A, AT complementation group C, AT complementation group D, AT complementation group E, AT mutated, AT protein, ATC, ATDC, ATE, ATM, ATM phospho S794, ATM_HUMAN, Ataxia telangiectasia mutated, Human phosphatidylinositol 3 kinase homolog, Serine protein kinase ATM, T cell prolymphocytic leukemia, TEL1, TPLL, p-ATM S794, p-ATM Ser794, AT1, ATA, ATM Ser794, Ataxia telangiectasia gene mutated in human beings |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ATM (Ser794) |
| Short name: |
ATM (Ser794) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ataxia telangiectasia mutated (Ser794) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AT1 and ATA and ATC and ATD and ATDC and ATE and TEL1 and TELO1, ATM and IDBG-629882 and ENSBTAG00000003111 and 526824, ATM and IDBG-70193 and ENSG00000149311 and 472, Atm and IDBG-165511 and ENSMUSG00000034218 and 11920, alcohol group as acceptor, alcohol group as acceptor and also this GO :0032403 : protein complex binding and also this GO :0035174 : histone serine kinase activity and also this GO :0046983 : protein dimerization activity and also this GO :0047485 : protein N-terminus binding, alcohol group as acceptor and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0030889 and negative regulation of B cell proliferation and biological process this GO :0032403 and protein complex binding and molecular function this GO :0035174 and histone serine kinase activity and molecular function this GO :0035404 and histone-serine phosphorylation and biological process this GO :0036092 and phosphatidylinositol-3-phosphate biosynthetic process and biological process this GO :0042159 and lipoprotein catabolic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043517 and positive regulation of DNA damage response, nuclei, signal transduction by p53 class mediator and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0047485 and protein N-terminus binding and molecular function this GO :0048599 and oocyte development and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0071044 and histone mRNA catabolic process and biological process this GO :0071480 and cellular response to gamma radiation and biological process this GO :0072434 and signal transduction involved in mitotic G2 DNA damage checkpoint and biological process this GO :0090399 and replicative senescence and biological process, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007094 and mitotic spindle assembly checkpoint and biological process this GO :0007131 and reciprocal meiotic recombination and biological process this GO :0007165 and signal transduction and biological process this GO :0007292 and female gamete generation and biological process this GO :0007420 and brain development and biological process this GO :0007507 and heart development and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0010212 and response to ionizing radiation and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016303 and 1-phosphatidylinositol-3-kinase activity and molecular function this GO :0016572 and histone phosphorylation and biological process this GO :0016772 and transferase activity, telomeric region and cellular component this GO :0001666 and response to hypoxia and biological process this GO :0001756 and somitogenesis and biological process this GO :0002331 and pre-B cell allelic exclusion and biological process this GO :0003677 and DNA binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004677 and DNA-dependent protein kinase activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005819 and spindle and cellular component this GO :0006281 and DNA repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006975 and DNA damage induced protein phosphorylation and biological process this GO :0006977 and DNA damage response, this GO :0000077 and DNA damage checkpoint and biological process this GO :0000723 and telomere maintenance and biological process this GO :0000724 and double-strand break repair via homolo this GO us recombination and biological process this GO :0000781 and chromosome, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004677 : DNA-dependent protein kinase activity and also this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016303 : 1-phosphatidylinositol-3-kinase activity and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004677 : DNA-dependent protein kinase activity, this GO :0005488 : binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016303 : 1-phosphatidylinositol-3-kinase activity, this GO :0016772 : transferase activity, this GO :0016773 : phosphotransferase activity, this GO :0032403 : protein complex binding, this GO :0035174 : histone serine kinase activity, this GO :0046983 : protein dimerization activity, this GO :0047485 : protein N-terminus binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0016773 : phosphotransferase activity, transferring phosphorus-containing groups and molecular function this GO :0016773 and phosphotransferase activity, ataxia telangiectasia mutated |
| Identity: |
795 |
| Gene: |
ATM |
More about : ATM |
| Long gene name: |
ATM serine/threonine kinase |
| Synonyms gene: |
ATA ATDC ATC ATD |
| Synonyms gene name: |
C and D) ataxia telangiectasia mutated , ataxia telangiectasia mutated (includes complementation groups A |
| Synonyms: |
TEL1 TELO1 |
| Synonyms name: |
TEL1, cerevisiae) , homolog (S, telomere maintenance 1 |
| Locus: |
11q22, 3 |
| Discovery year: |
1995-07-07 |
| GenBank acession: |
AB209133 |
| Entrez gene record: |
472 |
| RefSeq identity: |
NM_000051 |
| Havana BLAST/BLAT: |
OTTHUMG00000166480 |
| Locus Specific Databases: |
Ataxia Telangiectasia Mutated (ATM) LOVD - Leiden Open Variation Database LRG_135 |