| Long name: |
AMPK alpha 2 (Ser176) Antibody |
| Also known as: |
AMPK alpha 2 (Ser176) Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
AMPK alpha 2 Ser176 |
| Specificity: |
This is a highly specific antibody against AMPK alpha 2 Ser176 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser176 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human AMPK alpha 2 around the phosphorylation site of Ser176 |
| Gene ID number: |
5563 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
AMPK is a heterotrimer consisting of an alpha catalytic subunit, AMPK is activated, AMPK is an important energy-sensing enzyme that monitors cellular energy status, In response to cellular metabolic stresses, Jul 2008], Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia, [provided by RefSeq, and non-catalytic beta and gamma subunits, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol, The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
5'-AMP-activated protein kinase catalytic subunit alpha-2, AAPK2_HUMAN, AMP activated protein kinase alpha 2 catalytic subunit, AMPK 2, AMPK alpha 2 chain, AMPK alpha 2 phospho Ser176, AMPK subunit alpha-2, AMPKalpha2, PRKAA, PRKAA 2, PRKAA2, Protein kinase AMP activated alpha 2 catalytic subunit, p-AMPK alpha 2 S176, p-AMPK alpha 2 Ser176, p-AMPK2phospho S176, AMPK alpha 2 phospho S176 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AMPK alpha 2 (Ser176) |
| Short name: |
AMPK alpha 2 (Ser176) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
AMPK a 2 (Ser176) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9377 |
| Gene: |
PRKAA2 |
More about : PRKAA2 |
| Long gene name: |
protein kinase AMP-activated catalytic subunit alpha 2 |
| Synonyms gene: |
PRKAA |
| Synonyms gene name: |
AMP-activated, alpha 2 catalytic subunit , protein kinase |
| Synonyms: |
AMPK AMPKa2 |
| Locus: |
1p32, 2 |
| Discovery year: |
1995-12-12 |
| GenBank acession: |
BC069823 |
| Entrez gene record: |
5563 |
| Pubmed identfication: |
7959015 |
| RefSeq identity: |
NM_006252 |
| Havana BLAST/BLAT: |
OTTHUMG00000008282 |