| Catalog number: | bs-12412R |
|---|---|
| Price: | 370 € |
| Supplier: | MBS Polyclonals |
| Product name: | SP1 (Thr453) Antibody |
| Quantity: | 100ug |
| Related search: |
| Long name: | SP1 (Thr453) Primary Polyclonal Antibody |
|---|---|
| Also known as: | SP1 (Thr453) PAb |
| Category: | Primary Antibodies |
| Conjugation: | Unconjugated |
| Target Antigen: | SP1 Thr453 |
| Specificity: | This is a highly specific antibody against SP1 Thr453 |
| Modification(s): | Phosphorylation |
| Modification site(s): | Thr453 |
| Clonality: | Polyclonal antibody |
| Clone number: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | KLH conjugated synthetic phosphopeptide derived from human TSFP1 around the phosphorylation site of Thr453 |
| Gene ID number: | 6667 |
| Tested Applications: | IF(IHC-P), IHC-P, WB |
| Recommended dilutions: | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: | Mouse, Rat, Human |
| Cross reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: | Erg-1 (also known as Zif268 or NGF1-A) (7), Evidence suggests that the early growth response gene, Sp1 belongs to a subgroup of transcription factors that are phosphorylated upon binding to promoter sequences, Sp1 was initially identified as a HeLa cell-derived factor that selectively activates in vitro transcription from the SV40 promoter and binds to the multiple GC boxes in the 21-bp repeated elements in SV40, The gene encoding human Sp1 maps to chromosome 12q13, The sequence specificity of DNA binding is conferred by Zn (II) fingers, may downregulate certain mammalian gene promoters by competing with Sp1 for binding to an overlapping binding motif, whereas a different region of Sp1 appears to regulate the affinity of DNA binding, which are often referred to as GC boxes, 1, Sp1 is a sequence-specific transcription factor that recognizes GGGGCGGGGC and closely related sequences |
| Purification method: | This antibody was purified via Protein A |
| Storage conditions: | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: | SP 1, SP1, SP1 T453, SP1_HUMAN, Sp1 transcription factor, Sp1 transcription factor isoform a, Specicity protein 1, TSFP 1, TSFP1, Transcription factor Sp1, p-SP1 phospho T453, p-TSFP1 phospho T453, SP1 Thr453 |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: | SP1 (Thr453) |
| Short name: | SP1 (Thr453) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | SP1 (Thr453) (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 11205 |
| Gene: | SP1 | More about : SP1 |
| Long gene name: | Sp1 transcription factor |
| Synonyms name: | specificity protein 1 |
| Locus: | 12q13, 13 |
| Discovery year: | 1991-06-04 |
| GenBank acession: | J03133 |
| Entrez gene record: | 6667 |
| Pubmed identfication: | 1662663 |
| Classification: | Sp transcription factors Zinc fingers C2H2-type |
| Havana BLAST/BLAT: | OTTHUMG00000170047 |
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