| Long name: |
ALEXA FLUOR 350 Conjugated, HES2 Polyclonal Antibody |
| Also known as: |
Anti-HES2 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
HES2 |
| Specificity: |
This is a highly specific antibody against HES2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HES2 |
| Gene ID Number: |
54626 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
HES1 and HES2 are expressed in a variety of adult and embryonic tissues, HES1-6, HES2 binds to both N and E box sites, HES3 is expressed exclusively in cerebellar Purkinje cells, HES6 inhibits HES1 activity, HES6 is produced in brain as well as in the limb buds of developing embryos, Most HES family members, Rather, The HES family members form a complex with TLE, The HES/TLE complex functions by directly binding to DNA, The mammalian homologues of Drosophila hairy and Enhancer of split are the HES gene family members, and HES5 is found solely in the nervous system, and this interaction is mediated by the carboxy terminal WRPW motif of the HES proteins, including HES1 and HES5, instead of interfering with activator proteins, preferentially bind to the N box (CACNAG) as opposed to the E box (CANNTG), the mammalian homologue of Groucho, thereby promoting transcription, which also encode bHLH transcriptional repressors that regulate myogenesis and neurogenesis, while HES6 does not bind DNA, The Drosophila hairy and Enhancer of split genes encode basic helix-loop-helix (bHLH) transcriptional repressors that function in the Notch signaling pathway and control segmentation and neural development during embryogenesis |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
bHLHb40 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
HES2 |
| Short name: |
HES2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, HES2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16005 |
| Gene: |
HES2 |
More about : HES2 |
| Long gene name: |
hes family bHLH transcription factor 2 |
| Synonyms gene name: |
hairy and enhancer of split 2 (Drosophila) |
| Locus: |
1p36, 31 |
| Discovery year: |
2004-11-12 |
| GenBank acession: |
AL031848 |
| Entrez gene record: |
54626 |
| Pubmed identfication: |
15254753 |
| RefSeq identity: |
NM_019089 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000000752 |