| Long name: |
ALEXA FLUOR 350 Conjugated, MGLUR2/3 Polyclonal Antibody |
| Also known as: |
Anti-MGLUR2/3 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MGLUR2/3 |
| Specificity: |
This is a highly specific antibody against MGLUR2/3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
150-200/879 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MGLUR3 |
| Gene ID Number: |
2912, 2913 |
| Swiss Prot: |
Q14832, Q14416 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
GRM6, GRM7 and GRM8, Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions, Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C, Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities, Group II includes GRM2 and GRM3 while Group III includes GRM4, The metabotropic glutamate receptors are a family of G protein-coupled receptors, and pharmacologic properties, putative signal transduction mechanisms, that have been divided into 3 groups on the basis of sequence homology, L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
GPRC1B mGlu2 MGLUR2 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
MGLUR2/3 |
| Short name: |
MGLUR2/3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, MGLUR2/3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4594 |
| Gene: |
GRM2 |
More about : GRM2 |
| Long gene name: |
glutamate metabotropic receptor 2 |
| Synonyms gene name: |
glutamate receptor, metabotropic 2 |
| Locus: |
3p21, 2 |
| Discovery year: |
1993-10-21 |
| GenBank acession: |
L35318 |
| Entrez gene record: |
2912 |
| Pubmed identfication: |
7620613 |
| Classification: |
Glutamate metabotropic receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000156902 |