| Long name: |
ALEXA FLUOR 647 Conjugated, TAZ Polyclonal Antibody |
| Also known as: |
Anti-TAZ PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TAZ |
| Specificity: |
This is a highly specific antibody against TAZ |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
15-70/400 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TAZ |
| Gene ID Number: |
25937 |
| Swiss Prot: |
Q9GZV5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Regulates embryonic stem-cell self-renewal, Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex, The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, promotes cell proliferation and epithelial-mesenchymal transition, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ, Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
TAZ DKFZp586I1419 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the TAZ Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
TAZ |
| Short name: |
TAZ Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, TAZ (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
24042 |
| Gene: |
WWTR1 |
More about : WWTR1 |
| Long gene name: |
WW domain containing transcription regulator 1 |
| Locus: |
3q25, 1 |
| Discovery year: |
2004-12-03 |
| GenBank acession: |
AK022036 |
| Entrez gene record: |
25937 |
| Pubmed identfication: |
11118213 15096513 |
| RefSeq identity: |
NM_015472 |
| Havana BLAST/BLAT: |
OTTHUMG00000159614 |