| Long name: |
FITC Conjugated, STRA6 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
STRA6 |
| Specificity: |
This is a highly specific antibody against STRA6 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human STRA6 |
| Gene ID number: |
64220 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Mutations in the gene encoding Stra6 cause Matthew-Wood Syndrome, Stra6 functions as a cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4), Stra6 is broadly expressed, Stra6 removes retinol from RBP/RPB4 and transports it across the plasma membrane, The Stra6 gene maps to chromosome 15q24, This syndrome is characterized by anophtalmia, Ultimately increasing cellular retinol uptake from the retinol-RBP complex, also known as Spear Syndrome, lung and diaphragm, mild facial dysmorphism and malformations of the heart, multi-pass cell membrane protein, where it is metabolized, with 4 named isoforms that exist as a result of alternative splicing events, 1, STRA6 is a 667 amino acid |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FLJ12541 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
STRA6 Conjugated |
| Short name: |
FITC Conjugated, STRA6 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, STRA6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30650 |
| Gene: |
STRA6 |
More about : STRA6 |
| Long gene name: |
stimulated by retinoic acid 6 |
| Synonyms gene name: |
stimulated by retinoic acid gene 6 homolog (mouse) stimulated by retinoic acid 6 homolog (mouse) |
| Synonyms name: |
retinol binding protein 4 receptor |
| Locus: |
15q24, 1 |
| Discovery year: |
2004-12-20 |
| GenBank acession: |
AF352728 |
| Entrez gene record: |
64220 |
| Pubmed identfication: |
17255476 17273977 |
| Havana BLAST/BLAT: |
OTTHUMG00000138998 |
| Locus Specific Databases: |
LOVD |