| Long name: |
PBX1 Primary Polyclonal Antibody |
| Also known as: |
PBX1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PBX1 |
| Specificity: |
This is a highly specific antibody against PBX1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PBX1 |
| Gene ID number: |
5087 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins, Additionally, Human pre-B cell acute leukemias are frequently associated with a t(1, Pbx 2 and Pbx 3 share 92% and 94% respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, Pbx 4 expression is confined to the testis, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines, Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing, Unlike other homeotic selector genes which are expressed transiently during development and differentiation, especially to spermatocytes in the pachytene stage of the first meiotic prophase, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products, which do not express Pbx 1, while all three proteins are quite divergent at their amino- and carboxy-termini, 19)(q23, 3) chromosomal rearrangement, Pbx 1, p13 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Homeo box protein PBX1, Homeo box protein PRL, Homeobox protein PBX 1, Homeobox protein PBX1, Homeobox protein PRL, MGC126627, PBX 1, PBX1_HUMAN, PRL, Pbx1, Pre B cell leukemia homeobox 1, Pre B cell leukemia transcription factor 1, Pre-B-cell leukemia transcription factor 1, DKFZp686B09108 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PBX1 |
| Short name: |
PBX1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
pre-B-cellular leukemia homeobox 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006694 and steroid biosynthetic process and biological process this GO :0007548 and sex differentiation and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0009954 and proximal/distal pattern formation and biological process this GO :0010971 and positive regulation of G2/M transition of mitotic cell cycle and biological process this GO :0030278 and regulation of ossification and biological process this GO :0030325 and adrenal gland development and biological process this GO :0030326 and embryonic limb morphogenesis and biological process this GO :0035162 and embryonic hemopoiesis and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048536 and spleen development and biological process this GO :0048538 and thymus development and biological process this GO :0048568 and embryonic organ development and biological process this GO :0048706 and embryonic skeletal system development and biological process, PBX1 and IDBG-104447 and ENSG00000185630 and 5087, PBX1 and IDBG-629771 and ENSBTAG00000013801 and 540688, Pbx1 and IDBG-203379 and ENSMUSG00000052534 and 18514, nuclei, protein heterodimerization activity, this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001655 and urogenital system development and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046982 : protein heterodimerization activity, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0043565 : sequence-specific DNA binding, this GO :0046982 : protein heterodimerization activity, pre-B-cell leukemia homeobox 1 |
| Identity: |
8632 |
| Gene: |
PBX1 |
More about : PBX1 |
| Long gene name: |
PBX homeobox 1 |
| Synonyms gene name: |
pre-B-cell leukemia transcription factor 1 pre-B-cell leukemia homeobox 1 |
| Locus: |
1q23, 3 |
| Discovery year: |
1990-09-10 |
| GenBank acession: |
M86546 |
| Entrez gene record: |
5087 |
| RefSeq identity: |
NM_002585 |
| Classification: |
TALE class homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000034307 |