| Long name: |
Stella/DPPA3 Primary Polyclonal Antibody |
| Also known as: |
Stella/DPPA3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Stella/DPPA3 |
| Specificity: |
This is a highly specific antibody against Stella/DPPA3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
100-150/159 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Stella/DPPA3 |
| Gene ID number: |
359787 |
| Swiss Prot: |
Q6W0C5 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also involved in chromatin condensation in oocytogenesis (By similarity), Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, Does not bind paternal chromatin, In zygotes, May be important for the totipotent/pluripotent states continuing through preimplantation development, Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation, which is mainly packed into protamine and does not contain much H3K9me2 mark, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process, Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DPPA3, Developmental pluripotency-associated protein 3, STELLAR, Stella-related protein, STELLA |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Stella/DPPA3 |
| Short name: |
Stella/DPPA3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Stella/DPPA3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19199 |
| Gene: |
DPPA3 |
More about : DPPA3 |
| Long gene name: |
developmental pluripotency associated 3 |
| Synonyms: |
Stella |
| Locus: |
12p13, 31 |
| Discovery year: |
2003-07-09 |
| GenBank acession: |
AY317075 |
| Entrez gene record: |
359787 |
| RefSeq identity: |
NM_199286 |
| Havana BLAST/BLAT: |
OTTHUMG00000168434 |