| Long name: |
TIE2 (Tyr1108) Primary Polyclonal Antibody |
| Also known as: |
TIE2 (Tyr1108) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TIE2 Tyr1108 |
| Specificity: |
This is a highly specific antibody against TIE2 Tyr1108 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Tyr1108 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human TIE2 around the phosphorylation site of Tyr1108 |
| Gene ID number: |
7010 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Defects in TEK are associated with inherited venous malformations, The ligand for the receptor is angiopoietin-1, This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats, and humans, rats, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis, TEK is closely related to the TIE receptor tyrosine kinase, The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Angiopoietin-1 receptor, CD202b, CD202b antigen, Endothelial tyrosine kinase, Endothelium specic receptor tyrosine kinase 2, Hyk, TEK tyrosine kinase endothelial, TIE 2, TIE2_HUMAN, Tek, Tunica interna endothelial cell kinase, Tyrosine kinase with Ig and EGF homology domains 2, Tyrosine protein kinase receptor TEK, Tyrosine protein kinase receptor TIE 2, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, VMCM, VMCM 1, VMCM1, Venous malformations multiple cutaneous and mucosal, endothelial, hTIE 2, hTIE2, hTIE2, p140 TEK, p140 TEK, tek tyrosine kinase, tek tyrosine kinase, p-TIE2 phospho Y1108 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TIE2 (Tyr1108) |
| Short name: |
TIE2 (Tyr1108) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TIE2 (Tyr1108) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11724 |
| Gene: |
TEK |
More about : TEK |
| Long gene name: |
TEK receptor tyrosine kinase |
| Synonyms gene: |
VMCM |
| Synonyms gene name: |
endothelial , multiple cutaneous and mucosal TEK tyrosine kinase, venous malformations |
| Synonyms: |
TIE2 TIE-2 VMCM1 CD202b |
| Locus: |
9p21, 2 |
| Discovery year: |
1994-05-24 |
| GenBank acession: |
L06139 |
| Entrez gene record: |
7010 |
| Pubmed identfication: |
1312667 7833915 |
| Classification: |
Fibronectin type III domain containing CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000019712 |