| Long name: |
Biotin Conjugated, TRAF1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TRAF1 |
| Specificity: |
This is a highly specific antibody against TRAF1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
366-416/416 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human TRAF1 |
| Gene ID number: |
7185 |
| Swiss Prot: |
Q13077 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Plays a role in the regulation of cell survival and apoptosis, The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2, The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14, Adapter molecule that regulates the activation of NF-kappa-B and JNK |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
EBI6 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TRAF1 Conjugated |
| Short name: |
Conjugated, TRAF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, tumor necrosis factor receptor-associated factor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, EBI6 and MGC:10353, TRAF1 and IDBG-638832 and ENSBTAG00000003012 and 540944, TRAF1 and IDBG-83153 and ENSG00000056558 and 7185, Traf1 and IDBG-163730 and ENSMUSG00000026875 and 22029, thioesterase binding, this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031996 and thioesterase binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :2001236 and regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0031996 : thioesterase binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0031996 : thioesterase binding, TNF receptor-associated factor 1 |
| Identity: |
12031 |
| Gene: |
TRAF1 |
More about : TRAF1 |
| Long gene name: |
TNF receptor associated factor 1 |
| Locus: |
9q33, 2 |
| Discovery year: |
1997-06-12 |
| GenBank acession: |
AK090468 |
| Entrez gene record: |
7185 |
| Pubmed identfication: |
8069916 |
| RefSeq identity: |
NM_005658 |
| Classification: |
TNF receptor associated factors |
| Havana BLAST/BLAT: |
OTTHUMG00000020578 |