| Category: |
Antibody |
| Concentration: |
pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRAF1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
Western blot: 1:1000 |
| Notes: |
Titration of the TRAF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This TRAF1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q13077 |
| Purity: |
Antigen affinity |
| Description: |
EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, TRAF proteins associate with, The expression of this protein can be induced by Epstein-Barr virus (EBV), The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), This protein and TRAF2 form a heterodimeric complex, Three transcript variants encoding two different isoforms have been found for this gene, and mediate the signal transduction from various receptors of the TNFR superfamily, and thus mediates the anti-apoptotic signals from TNF receptors, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB, The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family |
| Immunogen: |
A portion of amino acids 55-83 from the human protein was used as the immunogen for this TRAF1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TRAF1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRAF1 |
| Short name: |
TRAF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
tumor necrosis factor receptor-associated factor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, EBI6 and MGC:10353, TRAF1 and IDBG-638832 and ENSBTAG00000003012 and 540944, TRAF1 and IDBG-83153 and ENSG00000056558 and 7185, Traf1 and IDBG-163730 and ENSMUSG00000026875 and 22029, thioesterase binding, this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0031996 and thioesterase binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :2001236 and regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0031996 : thioesterase binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0031996 : thioesterase binding, TNF receptor-associated factor 1 |
| Identity: |
12031 |
| Gene: |
TRAF1 |
More about : TRAF1 |
| Long gene name: |
TNF receptor associated factor 1 |
| Synonyms: |
EBI6 |
| Locus: |
9q33, 2 |
| Discovery year: |
1997-06-12 |
| GenBank acession: |
AK090468 |
| Entrez gene record: |
7185 |
| Pubmed identfication: |
8069916 |
| RefSeq identity: |
NM_005658 |
| Classification: |
TNF receptor associated factors |
| Havana BLAST/BLAT: |
OTTHUMG00000020578 |