| Long name: |
CHRND Primary Polyclonal Antibody |
| Also known as: |
CHRND PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CHRND |
| Specificity: |
This is a highly specific antibody against CHRND |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CHRND |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
AChR delta, FCCMS, Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system, Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, SCCMS or CHRND, The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, These transmembrane receptors change conformation in response to their cognate neurotransmitter, Two important members of this family are the nicotinic acetylcholine and glutamate receptors, allowing ions to move through the pore, also known as CMS2A, an enzyme that rapidly hydrolyzes acetylcholine, both of which are composed of five homologous subunits forming a transmembrane aqueous pore, congenital myasthenic syndrome slow-channel type (SCCMS) and congenital myasthenic syndrome fast-channel type (FCCMS), is a 517 amino acid multi-pass membrane protein that is associated with lethal type multiple pterygium syndrome, Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ACHD_HUMAN, ACHRD, Acetylcholine receptor subunit delta, CHRND, CMS2A, Cholinergic receptor, FCCMS, Nicotinic acetylcholine receptor delta polypeptide precursor, SCCMS, delta polypeptide, nicotinic, Acetylcholine receptor delta subunit |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CHRND |
| Short name: |
CHRND Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CHRND (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1965 |
| Gene: |
CHRND |
More about : CHRND |
| Long gene name: |
cholinergic receptor nicotinic delta subunit |
| Synonyms gene: |
ACHRD |
| Synonyms gene name: |
cholinergic receptor, delta (muscle) cholinergic receptor, delta cholinergic receptor, nicotinic, nicotinic, nicotinic delta |
| Synonyms name: |
acetylcholine receptor, delta (muscle) , nicotinic |
| Locus: |
2q37, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X55019 |
| Entrez gene record: |
1144 |
| Classification: |
Cholinergic receptors nicotinic subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000133261 |