| Long name: |
TRPV3 Primary Polyclonal Antibody |
| Also known as: |
TRPV3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TRPV3 |
| Specificity: |
This is a highly specific antibody against TRPV3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRPV3 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Human TRPV3 is expressed in skin, In addition, It is abundantly expressed in kidney, TRPV3 associates with VR-1 and may modulate VR-1 activity, TRPV3 is co-expressed in dosal root ganglion neurons with VR-1, TRPV5 controls the rate-limiting step of vitamin D3-regulated Ca2+ reabsorption in kidney and intestine, The 729 amino acid TRPV5 (ECAC1) protein comprises six transmembrane domains, an N-linked glycosylation site and three ankyrin repeat regions, and at lower levels in testis, brain, capsaicin-insensitive TRPV3 is expressed at warm temperatures, colon and rectum, dorsal root ganglion, expression increases in response to noxious temperatures, including temperature sensation and vasoregulation Transcribed from a gene adjacent to VR-1, jejunum and pancreas, multiple potential phosphorylation sites, placenta, prostate, spinal cord and brain, the 5â, the thermal-sensitive, tongue, trigeminal ganglion, &euro, &trade, -flanking region of TRPV5 contains four putative vitamin D3-responsive elements, Transient receptor potential (TRP) proteins are cation-sensitive channels that modulate a myriad of cellular functions |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
MGC124324, MGC124325, TRPV3_HUMAN, Transient receptor potential cation channel subfamily V member 3, TrpV3, Trpv3 heat sensitive channel, VRL 3, VRL-3, VRL3, Vanilloid receptor 3, Vanilloid receptor like 3, Vanilloid receptor-like 3, vanilloid receptor-related osmotically activated channel protein, 1110036I10Rik |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TRPV3 |
| Short name: |
TRPV3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TRPV3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
18084 |
| Gene: |
TRPV3 |
More about : TRPV3 |
| Long gene name: |
transient receptor potential cation channel subfamily V member 3 |
| Synonyms gene name: |
member 3 , subfamily V, transient receptor potential cation channel |
| Synonyms: |
VRL3 |
| Locus: |
17p13, 2 |
| Discovery year: |
2002-07-05 |
| GenBank acession: |
AF514998 |
| Entrez gene record: |
162514 |
| Pubmed identfication: |
12016205 12077606 16382100 |
| RefSeq identity: |
NM_145068 |
| Classification: |
Ankyrin repeat domain containing Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000090695 |