| Long name: |
Biotin Conjugated, GABRA6/GABA A Receptor alpha 6 Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GABRA6/GABA A Receptor alpha 6 |
| Specificity: |
This is a highly specific antibody against GABRA6/GABA A Receptor alpha 6 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human GABRA6/GABA A Receptor alpha 6 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
-2, Both GABAA and GABAC are ligand-gated ion channels, GABA T-2 and GABA T-3 (also designated GAT-1, GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC, GABA transporters have also been identified and include GABA T-1, GABAA R beta 1-3, GABAA R delta, GABAA R gamma , GABAA R gamma 1-3, In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing, Members of the GABAA receptor family include GABAA R alpha 1-6, The GABA transporters function to terminate GABA action, The GABAB family is composed of GABAB R1 alpha and GABAB R1 beta, and -3), function to catalyze the production of GABA (gamma-aminobutyric acid), glutamate decarboxylases, however, they are structurally and functionally distinct, GAD-65 and GAD-67 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GABRA6/GABA A Receptor alpha 6 Conjugated |
| Short name: |
Conjugated, GABRA6/GABA A Receptor alpha 6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, GABRA6/GABA A Receptor a 6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4080 |
| Gene: |
GABRA6 |
More about : GABRA6 |
| Long gene name: |
gamma-aminobutyric acid type A receptor alpha6 subunit |
| Synonyms gene name: |
alpha 6 , gamma-aminobutyric acid (GABA) A receptor |
| Synonyms name: |
GABA(A) receptor, alpha 6 |
| Locus: |
5q34 |
| Discovery year: |
1994-04-20 |
| Entrez gene record: |
2559 |
| Pubmed identfication: |
8020978 |
| Classification: |
Gamma-aminobutyric acid type A receptor subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000130351 |