| Long name: |
Biotin Conjugated, MGLUR3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MGLUR3 |
| Specificity: |
This is a highly specific antibody against MGLUR3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human Metabotropic Glutamate Receptor 3 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
2, 3, 4 and one zeta subunit, Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7, The NMDA receptors consist of five subunits: epsilion 1, The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions, The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution, both of which contain glutamate-gated, cation-specific ion channels, neural development and neurodegeneration, Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
GPRC1C mGlu3 MGLUR3 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MGLUR3 Conjugated |
| Short name: |
Conjugated, MGLUR3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, MGLUR3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4595 |
| Gene: |
GRM3 |
More about : GRM3 |
| Long gene name: |
glutamate metabotropic receptor 3 |
| Synonyms gene name: |
glutamate receptor, metabotropic 3 |
| Locus: |
7q21, 11-q21, 12 |
| Discovery year: |
1993-10-21 |
| Entrez gene record: |
2913 |
| Pubmed identfication: |
8824806 |
| Classification: |
Glutamate metabotropic receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000022884 |