| Long name: |
FOG2 Primary Polyclonal Antibody |
| Also known as: |
FOG2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
FOG2 |
| Specificity: |
This is a highly specific antibody against FOG2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FOG2 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
FOG-2 inhibits GATA-4 transcriptional activity, FOG-2 is able to both positively and negatively influence GATA mediated transcription, FOG-2 is predominantly expressed in heart, FOG/GATA-1 complexes are required for erythroid and megakaryocyte maturation, GATA-4 and GATA-6, In cardiomyocytes and fibroblasts, These complexes involve the association between multiple zinc fingers on the FOG proteins and the N-terminal zinc finger of GATA proteins, While FOG cooperatively regulates GATA-1 induced transcription, and it preferentially participates in the regulation of GATA-3, and they promote differentiation during embryonic development, are zinc finger proteins that interact with the GATA family of transcriptional regulators, including FOG (friend of GATA-1) and FOG-2, neurons and gonads, suggesting that the observed effects of FOG-2 are context specific and vary between cellular systems, yet FOG-2 restores GATA-1 mediated transcription in erythroid cultures deficient in FOG, The FOG family of transcriptional cofactors |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FOG2_HUMAN, Friend of GATA 2, Friend of GATA protein 2, Friend of GATA2 , ZFPM2, Zinc finger protein 89B, Zinc finger protein M2, Zinc finger protein ZFPM2, Zinc finger protein multitype 2 , hFOG-2 , FOG-2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FOG2 |
| Short name: |
FOG2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FOG2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16700 |
| Gene: |
ZFPM2 |
More about : ZFPM2 |
| Long gene name: |
FOG family member 2 , zinc finger protein |
| Synonyms gene name: |
multitype 2 , zinc finger protein |
| Synonyms: |
FOG2 hFOG-2 ZNF89B ZC2HC11B |
| Locus: |
8q23 |
| Discovery year: |
2002-11-26 |
| GenBank acession: |
AF119334 |
| Entrez gene record: |
23414 |
| Pubmed identfication: |
9927675 10438528 |
| Classification: |
Zinc fingers C2H2-type Zinc fingers C2HC-type |
| Havana BLAST/BLAT: |
OTTHUMG00000164818 |