| Long name: |
ALEXA FLUOR 647 Conjugated, Meis homeobox 3 Polyclonal Antibody |
| Also known as: |
Anti-Meis homeobox 3 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Meis homeobox 3 |
| Specificity: |
This is a highly specific antibody against Meis homeobox 3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Meis homeobox 3 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Rat, Mouse |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Both Meis1 and Meis2 (also known as Meis-related gene 1 or Mrg1) are members of the TALE (â, Hox proteins are involved in regulating tissue patterning during development, In addition to binding with Hox proteins, In the pancreas, Like Hox and Pbx proteins, Meis1 also forms heterodimers with the ubiquitously expressed Pbx proteins, Meis1 is implicated in oncogenesis, Meis2 and Meis3 (also designated Mrg1 and Mrg2, Meis2 preferentially associates with Pbx1, Pbx and Meis families of transcription factors form heteromeric complexes and bind DNA through specific homeobox domains, Pbx2 and Pbx3, Pdx1, The Hox proteins, Two Meis-related proteins, and are also expressed in lineage- and stage-specific patterns during adult hematopoietic differentiation and in leukemias, and these complexes contain distinct DNA-binding specificities, and together they associate with the pancreas-specific homeodomain factor, as it is overexpressed as a result of adjacent retroviral insertion in BHX-2 myeloid leukemias, have a low intrinsic binding affinity for DNA and are instead associated into cooperative DNA binding complexes with Pbx or the Pbx- related Meis proteins, including Pbx1, possess largely similar sequence identity with Meis1 and are expressed in normal tissues and myeloid leukemias, respectively), to repress Pdx1-induced transcriptional activation, which include paralog groups 1-10, which result in an enhanced Hox-DNA binding affinity and an increased selectivity for the binding site, &euro, &euro, &oelig, Hox, three amino acid loop extensionâ, ) family of homeodomain-containing proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Meis homeobox 3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Meis homeobox 3 |
| Short name: |
Meis homeobox 3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, Meis homeobox 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17638 |
| Gene: |
MEIS3P2 |
More about : MEIS3P2 |
| Long gene name: |
Meis homeobox 3 pseudogene 2 |
| Synonyms gene name: |
Meis1 homolog 3 (mouse) pseudogene 2 |
| Locus: |
17p11, 2 |
| Discovery year: |
2005-12-23 |
| Entrez gene record: |
257468 |
| RefSeq identity: |
NG_002418 |
| Classification: |
TALE class homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000059559 |