| Long name: |
Cy7 Conjugated, MAP3K4/MEK kinase-4 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MAP3K4/MEK kinase-4 |
| Specificity: |
This is a highly specific antibody against MAP3K4/MEK kinase-4 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human MAP3K4/MEK kinase-4 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ASK 1 (MEK kinase-5) and MAP3K6 (MEK kinase-6), ASK1 activates both MEK-4 and MEK-3/MEK-6 pathways, Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3, JNK and p38, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), MEK kinase-1, MEK kinase-1 has been shown to phosphorylate MEK-1 via Raf-independent pathway, MEK kinase-2, MEK kinase-3, MEK kinase-4, MEK kinase-4 has been shown to specifically activate the JNK path-way, MKKKs, Mos, Raf-B, The MEK kinases (also designated MAP kinase kinase kinases, The MEK kinases include Raf-1, These activated MEKs in turn phosphorylate and activate the MAP kinases, including ERK, Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
MTK1 MAPKKK4 KIAA0213 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
MAP3K4/MEK kinase-4 Conjugated |
| Short name: |
Conjugated, MAP3K4/MEK kinase-4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, mitogen-activated protein phosphorylation catalyst kinase phosphorylation catalyst 4/MEK phosphorylation catalyst-4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, MAP3K4 and IDBG-635619 and ENSBTAG00000020079 and 511779, MAP3K4 and IDBG-98770 and ENSG00000085511 and 4216, MAPKKK4 and MEKK 4 and MEKK4 and MTK1 and PRO0412, Map3k4 and IDBG-136472 and ENSMUSG00000014426 and 26407, this GO :0000165 and MAPK cascade and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0001890 and placenta development and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004709 and MAP kinase kinase kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0010225 and response to UV-C and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004709 : MAP kinase kinase kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004709 : MAP kinase kinase kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0046872 : metal ion binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0046872 : metal ion binding, transferring phosphorus-containing groups and molecular function this GO :0019100 and male germ-line sex determination and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0043507 and positive regulation of JUN kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0060718 and chorionic trophoblast cell differentiation and biological process this GO :1900745 and positive regulation of p38MAPK cascade and biological process, mitogen-activated protein kinase kinase kinase 4 |
| Identity: |
6856 |
| Gene: |
MAP3K4 |
More about : MAP3K4 |
| Long gene name: |
mitogen-activated protein kinase kinase kinase 4 |
| Synonyms gene: |
MEKK4 |
| Locus: |
6q26 |
| Discovery year: |
1997-11-14 |
| GenBank acession: |
AF002715 |
| Entrez gene record: |
4216 |
| Pubmed identfication: |
9305639 |
| Classification: |
Mitogen-activated protein kinase kinase kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000015968 |