| Long name: |
Cy5, 5 Conjugated, LIM kinase 1 + 2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
LIM kinase 1 + 2 |
| Specificity: |
This is a highly specific antibody against LIM kinase 1 + 2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human LIM kinase 1 + 2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
LIMK1 is highly active in the brain and spinal chord, LIMK1 is specifically stimulated by Rac, LIMK1 may play an important role in areas of the brain that are responsible for processing visual-spatial information (visuospatial constructive cognition), Rho and Cdc42, These parts of the brain are important for visualizing an object as a set of parts and performing tasks such as writing, They can phosphorylate an actin-binding protein, and assembling puzzles, cofilin which binds to actin monomers and polymers and promotes the disassembly of actin filament, constructing models, drawing, one of the Rho family proteins, suggesting that two distinct pathways exist in the Rho family driven actin cytoskeleton dynamics, through control of the organization of actin filaments, where it is believed to be involved in the development of nerve cells whilst LIMK2 is ubiquitously expressed in many adult tissues, while LIMK2 activity is activated under the control of other Rho family members, LIMK 1 and 2 likely regulate aspects of the cytoskeleton, The phosphorylation of cofilin via LIMK inactivates this potential |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
LIM Enh |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
LIM kinase 1 + 2 Conjugated |
| Short name: |
Conjugated, LIM kinase 1 + 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, LIM phosphorylation catalyst 1 and 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17468 |
| Gene: |
PDLIM5 |
More about : PDLIM5 |
| Long gene name: |
PDZ and LIM domain 5 |
| Locus: |
4q22, 3 |
| Discovery year: |
2005-01-12 |
| GenBank acession: |
AF061258 |
| Entrez gene record: |
10611 |
| Pubmed identfication: |
15346770 |
| Classification: |
LIM domain containing PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130973 |