| Long name: |
FITC Conjugated, DYX2/KIAA0319 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DYX2/KIAA0319 |
| Specificity: |
This is a highly specific antibody against DYX2/KIAA0319 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human DYX2/KIAA0319 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
DYX2 is highly expressed in brain cortex, Defects in the gene encoding DYX2 may be the cause of dyslexia type 2, In DYX2, There are three isoforms of DYX2 that are produced as a result of alternative splicing events, When overexpressed, a relatively common disorder that is characterized by reading performance impairment in the absence of sensory or neurologic disability, amygdala, cerebellum, it is likely that its PKD domains mediate the interaction between neurons and glial fibers during neuronal migration, putamen and hippocampus, suggesting that it is endocytosed and recycled, this plasma membrane protein colocalizes with EEA1 (early endosome antigen 1) in large intracellular vesicles, which are usually found in the extracellular regions of proteins and are involved in protein-protein interactions, DYX2 is a 1072 amino acid single-pass transmembrane protein that contains one MANSC domain and two PKD (Polycystic Kidney Disease) domains |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DYX2/KIAA0319 Conjugated |
| Short name: |
FITC Conjugated, DYX2/KIAA0319 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, DYX2/KIAA0319 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3109 |
| Gene: |
DYX2 |
More about : DYX2 |
| Long gene name: |
dyslexia susceptibility 2 |
| Locus: |
6 |
| Discovery year: |
1996-07-19 |
| Pubmed identfication: |
7939663 |