| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DYX2/KIAA0319 |
| Specificity: |
This antibody reacts specifically with DYX2/KIAA0319 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DYX2/KIAA0319 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
DYX2 is highly expressed in brain cortex, Defects in the gene encoding DYX2 may be the cause of dyslexia type 2, In DYX2, There are three isoforms of DYX2 that are produced as a result of alternative splicing events, When overexpressed, a relatively common disorder that is characterized by reading performance impairment in the absence of sensory or neurologic disability, amygdala, cerebellum, it is likely that its PKD domains mediate the interaction between neurons and glial fibers during neuronal migration, putamen and hippocampus, suggesting that it is endocytosed and recycled, this plasma membrane protein colocalizes with EEA1 (early endosome antigen 1) in large intracellular vesicles, which are usually found in the extracellular regions of proteins and are involved in protein-protein interactions, DYX2 is a 1072 amino acid single-pass transmembrane protein that contains one MANSC domain and two PKD (Polycystic Kidney Disease) domains |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
DYX2/KIAA0319 Polyclonal Antibody |
| Other name: |
Anti-DYX2/KIAA0319 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DYX2/KIAA0319 |
| Short name: |
Anti-DYX2/KIAA0319 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-DYX2/KIAA0319 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3109 |
| Gene: |
DYX2 |
More about : DYX2 |
| Long gene name: |
dyslexia susceptibility 2 |
| Locus: |
6 |
| Discovery year: |
1996-07-19 |
| Pubmed identfication: |
7939663 |