| Long name: |
ALEXA FLUOR 647 Conjugated, Jarid2/Jumonji Polyclonal Antibody |
| Also known as: |
Anti-Jarid2/Jumonji PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Jarid2/Jumonji |
| Specificity: |
This is a highly specific antibody against Jarid2/Jumonji |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
315-365/1246 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Jarid2/Jumonji |
| Gene ID Number: |
3720 |
| Swiss Prot: |
Q92833 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts by modulating histone methyltransferase activity and promoting the recruitment of histone methyltransferase complexes to their target genes, Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5, Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells, Does not have histone demethylase activity but regulates activity of various histone methyltransferase complexes, In cardiac cells, In embryonic stem cells, Participates in the negative regulation of cell proliferation signaling, including heart and liver development, it associates with the PRC2 complex and inhibits trimethylation of 'Lys-27' of histone H3 (H3K27me3) by the PRC2 complex, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases, neural tube fusion process and hematopoiesis, thereby playing a key role in differentiation of embryonic stem cells and normal development, Regulator of histone methyltransferase complexes that plays an essential role in embryonic development |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
JARID2, Jumonji/ARID domain-containing protein 2, Protein Jumonji, JMJ |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Jarid2/Jumonji Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
Jarid2/Jumonji |
| Short name: |
Jarid2/Jumonji Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, AT rich interactive domain 2/Jumonji (Antibody to), jumonji |
| Alternative technique: |
antibodies |