| Long name: |
HELT Primary Polyclonal Antibody |
| Also known as: |
HELT PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
HELT |
| Specificity: |
This is a highly specific antibody against HELT |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HELT |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Containing a basic helix-loop-helix (bHLH) domain and an Orange domain, HESL (HES-like), HESL exists as two isoforms produced by alternative splicing events, HESL is considered a transcriptional repressor that binds to the canonical E box sequence 5'-CACGCG-3', HESL self-associates and interacts with HES5 and HRT2, The Notch signaling pathway is thought to maintain stem cells through transcriptional activation of HES/HEY family members to repress tissue-specific transcription factors, also known as Mgn or HELT (HES/HEY-like transcription factor), is a 327 amino acid nuclear protein belonging to the HEY family, The Drosophila hairy and Enhancer of split genes encode basic helix-loop-helix (bHLH) transcriptional repressors that function in the Notch signaling pathway and control segmentation and neural development during embryogenesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
HCM1228, HELT, HELT_HUMAN, HES like , HES/HEY like transcription factor, HES/HEY-like transcription factor, HESL, Heslike , Hey like transcription factor, Hey like transcription factor zebrafish, Hey like transcriptional repressor, Megane bHLH factor, Mgn, Hairy and enhancer of split-related protein HELT |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
HELT |
| Short name: |
HELT Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HELT (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
33783 |
| Gene: |
HELT |
More about : HELT |
| Long gene name: |
helt bHLH transcription factor |
| Synonyms gene name: |
Hey-like transcription factor (zebrafish) HES/HEY-like transcription factor |
| Synonyms: |
HESL HCM1228 Mgn bHLHb44 MEGANE |
| Synonyms name: |
megane bHLH factor HES-like |
| Locus: |
4q35, 1 |
| Discovery year: |
2008-04-21 |
| GenBank acession: |
BC144567 |
| Entrez gene record: |
391723 |
| Pubmed identfication: |
14764602 17611227 |
| RefSeq identity: |
NM_001300781 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000160484 |