| Long name: |
FITC Conjugated, GSS/Glutathione Synthetase Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GSS/Glutathione Synthetase |
| Specificity: |
This is a highly specific antibody against GSS/Glutathione Synthetase |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Glutathione Syntase |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
5-oxoprolinuria (pyroglutamic aciduria), A missense mutation in the gene encoding GSS leads to a GSS deficiency restricted to erythrocytes, Although Southern blot and gene analysis suggest that GSS may be the only member of a unique family, Although Southern blot and gene analysis suggest that GSS may be the only member of a unique family, An inherited autosomal recessive disorder, GSS consists of three loops projecting from an antiparallel â, GSS consists of three loops projecting from an antiparallel â, GSS is expressed in hemocytes and nucleated cells, GSS is expressed in hemocytes and nucleated cells, GSS occurs as a homodimer, GSS occurs as a homodimer, GSS produces Glutathione from &, In an ATP-dependent reaction, Partial hepatectomy, There are two steps in the production of Glutathione, There are two steps in the production of Glutathione, a parallel â, a parallel â, begining with &, begining with GSS (Glutathione synthetase) is a 474 amino acid protein encoded by the gene located at human chromosome 20q11, buthionine sulfoximine, diethyl maleate, hemolytic anemia, including the brain, including the brain, is caused by GSS deficiencies, metabolic acidosis and urinary excretion of 5-oxoproline, tert-butylhaydroquinone and thioacetamide increase the ex-pression of GSS, the crystal structure indicates that GSS belongs to the ATP-GRASP superfamily, the crystal structure indicates that GSS belongs to the ATP-GRASP superfamily, which causes an increase in Glutathione levels, which causes only hemolytic anemia, which leads to central nervous system damage, which provide access to the ATP-binding site, which provide access to the ATP-binding site, &circ, &circ, &circ, &circ, «, «, «, «, -GCS and ending with GSS, -GCS and ending with GSS, -glutamylcysteine and glycine precursors, -sheet, -sheet, -sheet and a lid of anti-parallel sheets, -sheet and a lid of anti-parallel sheets, 2, 2, GSS (Glutathione synthetase) is a 474 amino acid protein encoded by the gene located at human chromosome 20q11, copy, copy |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GSS/Glutathione Synthetase Conjugated |
| Short name: |
FITC Conjugated, GSS/Glutathione Synthetase Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, glutathione synthetase/GSH Synthetase (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cytoplasm, GSHS and HEL-S-64p and HEL-S-88n, GSS and IDBG-641979 and ENSBTAG00000003504 and 525059, GSS and IDBG-69124 and ENSG00000100983 and 2937, Gss and IDBG-210630 and ENSMUSG00000027610 and 14854, glutathione binding, this GO :0000287 and magnesium ion binding and molecular function this GO :0004363 and glutathione synthase activity and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006520 and cellular amino acid metabolic process and biological process this GO :0006750 and glutathione biosynthetic process and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007399 and nervous system development and biological process this GO :0007568 and aging and biological process this GO :0009410 and response to xenobiotic stimulus and biological process this GO :0016594 and glycine binding and molecular function this GO :0031667 and response to nutrient levels and biological process this GO :0034612 and response to tumor necrosis factor and biological process this GO :0042277 and peptide binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043200 and response to amino acid and biological process this GO :0043295 and glutathione binding and molecular function this GO :0044281 and small molecule metabolic process and biological process this GO :0046686 and response to cadmium ion and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :1901687 and glutathione derivative biosynthetic process and biological process, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0004363 : glutathione synthase activity and also this GO :0005524 : ATP binding and also this GO :0016594 : glycine binding and also this GO :0042277 : peptide binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043295 : glutathione binding, this GO :0004363 : glutathione synthase activity, this GO :0005524 : ATP binding, this GO :0016594 : glycine binding, this GO :0042277 : peptide binding, this GO :0042803 : protein homodimerization activity, this GO :0043295 : glutathione binding, glutathione synthetase |
| Identity: |
4624 |
| Gene: |
GSS |
More about : GSS |
| Long gene name: |
glutathione synthetase |
| Locus: |
20q11, 22 |
| Discovery year: |
1991-05-01 |
| Entrez gene record: |
2937 |
| Pubmed identfication: |
8825653 |
| Havana BLAST/BLAT: |
OTTHUMG00000032315 |