| Long name: |
Cy5, 5 Conjugated, GDF6 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GDF6 |
| Specificity: |
This is a highly specific antibody against GDF6 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human GDF6 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
(5), GDF-1 expression is almost exclusively restricted to the central nervous system and mediates cell differentiation events during embryonic development (3), GDF-3 is detectable in bone marrow, GDF-5 (also designated CDMP-1) has been shown to induce activation of plasminogen activator, GDF-5 mutations have been identified in mice with the mutation brachypodism (bp), GDF-6 and GDF-7 are closely related to GDF-5 (6), GDF-8 has been shown to be a negative regulator of skeletal muscle mass (1), It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation, Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis (1), Neither GDF-3 (Vgr-2) nor GDF-9 contains the conserved cysteine residue which is found in most other TGF superfamily members, a mutation which affects the length and number of bones in limbs (6), spleen, thereby inducing angiogenesis, thymus and adipose tissue, whereas GDF-9 has only been detected in ovary (4), 2), Growth/differentiation factors (GDFs) are members of the TGF superfamily (1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
BMP13 KFS KFS1 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
GDF6 Conjugated |
| Short name: |
Conjugated, GDF6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, growth differentiation factor 6 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0060389 and pathway-restricted SMAD protein phosphorylation and biological process this GO :1990009 and retinal cell apoptotic process and biological process, Extracellular, GDF6 and IDBG-29375 and ENSG00000156466 and 392255, Gdf6 and IDBG-129105 and ENSMUSG00000051279 and 242316, protein homodimerization activity, this GO :0005125 and cytokine activity and molecular function this GO :0005615 and extracellular space and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008083 and growth factor activity and molecular function this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0032924 and activin receptor signaling pathway and biological process this GO :0040007 and growth and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045893 and positive regulation of transcription, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0008083 : growth factor activity and also this GO :0042803 : protein homodimerization activity, this GO :0008083 : growth factor activity, this GO :0042803 : protein homodimerization activity, 29849 and IDBG-645217 and ENSBTAG00000007687 and 407175, growth differentiation factor 6 |
| Identity: |
4221 |
| Gene: |
GDF6 |
More about : GDF6 |
| Long gene name: |
growth differentiation factor 6 |
| Synonyms gene: |
SGM1 |
| Synonyms gene name: |
segmentation syndrome 1 |
| Locus: |
8q22, 1 |
| Discovery year: |
1999-04-23 |
| Entrez gene record: |
392255 |
| Pubmed identfication: |
10022976 18425797 |
| RefSeq identity: |
NM_001001557 |
| Havana BLAST/BLAT: |
OTTHUMG00000164710 |