| Long name: |
ALEXA FLUOR 647 Conjugated, GDF6 Polyclonal Antibody |
| Also known as: |
Anti-GDF6 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GDF6 |
| Specificity: |
This is a highly specific antibody against GDF6 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GDF6 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
(5), GDF-1 expression is almost exclusively restricted to the central nervous system and mediates cell differentiation events during embryonic development (3), GDF-3 is detectable in bone marrow, GDF-5 (also designated CDMP-1) has been shown to induce activation of plasminogen activator, GDF-5 mutations have been identified in mice with the mutation brachypodism (bp), GDF-6 and GDF-7 are closely related to GDF-5 (6), GDF-8 has been shown to be a negative regulator of skeletal muscle mass (1), It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation, Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis (1), Neither GDF-3 (Vgr-2) nor GDF-9 contains the conserved cysteine residue which is found in most other TGF superfamily members, a mutation which affects the length and number of bones in limbs (6), spleen, thereby inducing angiogenesis, thymus and adipose tissue, whereas GDF-9 has only been detected in ovary (4), 2), Growth/differentiation factors (GDFs) are members of the TGF superfamily (1 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
BMP13 KFS KFS1 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the GDF6 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
GDF6 |
| Short name: |
GDF6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, growth differentiation factor 6 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, DNA-templated and biological process this GO :0060389 and pathway-restricted SMAD protein phosphorylation and biological process this GO :1990009 and retinal cell apoptotic process and biological process, Extracellular, GDF6 and IDBG-29375 and ENSG00000156466 and 392255, Gdf6 and IDBG-129105 and ENSMUSG00000051279 and 242316, protein homodimerization activity, this GO :0005125 and cytokine activity and molecular function this GO :0005615 and extracellular space and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008083 and growth factor activity and molecular function this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0032924 and activin receptor signaling pathway and biological process this GO :0040007 and growth and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045893 and positive regulation of transcription, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0008083 : growth factor activity and also this GO :0042803 : protein homodimerization activity, this GO :0008083 : growth factor activity, this GO :0042803 : protein homodimerization activity, 29849 and IDBG-645217 and ENSBTAG00000007687 and 407175, growth differentiation factor 6 |
| Identity: |
4221 |
| Gene: |
GDF6 |
More about : GDF6 |
| Long gene name: |
growth differentiation factor 6 |
| Synonyms gene: |
SGM1 |
| Synonyms gene name: |
segmentation syndrome 1 |
| Locus: |
8q22, 1 |
| Discovery year: |
1999-04-23 |
| Entrez gene record: |
392255 |
| Pubmed identfication: |
10022976 18425797 |
| RefSeq identity: |
NM_001001557 |
| Havana BLAST/BLAT: |
OTTHUMG00000164710 |